Literature DB >> 25036670

Anti-proliferative activity of 6-O-acyl-D-allose against the human leukemia MOLT-4F cell line.

Ryo C Yanagita1, Katsuya Kobashi, Chisa Ogawa, Yoshiki Ashida, Haruka Yamaashi, Yasuhiro Kawanami.   

Abstract

The anti-proliferative activities of the 6-O-acyl derivatives of D-allose against the human leukemia MOLT-4F cell line were examined. The activity of the 6-O-dodecanoyl derivative (3) was approximately 30 times stronger than that of D-allose. An evaluation of the derivatives of 3 that occurred in a furanose form revealed the pyranose forms of 3 to be important for the anti-proliferative activity.

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Keywords:  anti-proliferative activity; cancer; d-allose; leukemia; rare sugar

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Year:  2014        PMID: 25036670     DOI: 10.1080/09168451.2014.882747

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN: 0916-8451            Impact factor:   2.043


  1 in total

1.  In Search of Effective Anticancer Agents-Novel Sugar Esters Based on Polyhydroxyalkanoate Monomers.

Authors:  Wojciech Snoch; Dawid Wnuk; Tomasz Witko; Jakub Staroń; Andrzej J Bojarski; Ewelina Jarek; Francisco J Plou; Maciej Guzik
Journal:  Int J Mol Sci       Date:  2021-07-05       Impact factor: 5.923

  1 in total

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