Literature DB >> 25036308

Allostery: A GPCR's back door.

Klaus Mohr1, Evi Kostenis1.   

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Year:  2014        PMID： 25036308     DOI： 10.1038/nchembio.1583

Source DB:  PubMed          Journal:  Nat Chem Biol        ISSN： 1552-4450            Impact factor:   15.040


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  9 in total

Review 1.  Biased signalling and allosteric machines: new vistas and challenges for drug discovery.

Authors:  Terry P Kenakin
Journal:  Br J Pharmacol       Date:  2012-03       Impact factor: 8.739

Review 2.  The structure and function of the glucagon-like peptide-1 receptor and its ligands.

Authors:  Dan Donnelly
Journal:  Br J Pharmacol       Date:  2012-05       Impact factor: 8.739

3.  Identification of an antithrombotic allosteric modulator that acts through helix 8 of PAR1.

Authors:  Louisa Dowal; Derek S Sim; James R Dilks; Price Blair; Sarah Beaudry; Bradley M Denker; Georgios Koukos; Athan Kuliopulos; Robert Flaumenhaft
Journal:  Proc Natl Acad Sci U S A       Date:  2011-01-31       Impact factor: 11.205

Review 4.  Insights into the structure of class B GPCRs.

Authors:  Kaspar Hollenstein; Chris de Graaf; Andrea Bortolato; Ming-Wei Wang; Fiona H Marshall; Raymond C Stevens
Journal:  Trends Pharmacol Sci       Date:  2013-12-18       Impact factor: 14.819

5.  A potentiator of orthosteric ligand activity at GLP-1R acts via covalent modification.

Authors:  Whitney M Nolte; Jean-Philippe Fortin; Benjamin D Stevens; Gary E Aspnes; David A Griffith; Lise R Hoth; Roger B Ruggeri; Alan M Mathiowetz; Chris Limberakis; David Hepworth; Philip A Carpino
Journal:  Nat Chem Biol       Date:  2014-07-06       Impact factor: 15.040

Review 6.  Recent advances in understanding GLP-1R (glucagon-like peptide-1 receptor) function.

Authors:  Cassandra Koole; Kavita Pabreja; Emilia E Savage; Denise Wootten; Sebastian G B Furness; Laurence J Miller; Arthur Christopoulos; Patrick M Sexton
Journal:  Biochem Soc Trans       Date:  2013-02-01       Impact factor: 5.407

7.  Novel small molecule glucagon-like peptide-1 receptor agonist stimulates insulin secretion in rodents and from human islets.

Authors:  Kyle W Sloop; Francis S Willard; Martin B Brenner; James Ficorilli; Kathleen Valasek; Aaron D Showalter; Thomas B Farb; Julia X C Cao; Amy L Cox; M Dodson Michael; Sonia Maria Gutierrez Sanfeliciano; Mark J Tebbe; Michael J Coghlan
Journal:  Diabetes       Date:  2010-09-07       Impact factor: 9.461

8.  Activation and allosteric modulation of a muscarinic acetylcholine receptor.

Authors:  Andrew C Kruse; Aaron M Ring; Aashish Manglik; Jianxin Hu; Kelly Hu; Katrin Eitel; Harald Hübner; Els Pardon; Celine Valant; Patrick M Sexton; Arthur Christopoulos; Christian C Felder; Peter Gmeiner; Jan Steyaert; William I Weis; K Christopher Garcia; Jürgen Wess; Brian K Kobilka
Journal:  Nature       Date:  2013-11-20       Impact factor: 49.962

9.  The allosteric vestibule of a seven transmembrane helical receptor controls G-protein coupling.

Authors:  Andreas Bock; Nicole Merten; Ramona Schrage; Clelia Dallanoce; Julia Bätz; Jessica Klöckner; Jens Schmitz; Carlo Matera; Katharina Simon; Anna Kebig; Lucas Peters; Anke Müller; Jasmin Schrobang-Ley; Christian Tränkle; Carsten Hoffmann; Marco De Amici; Ulrike Holzgrabe; Evi Kostenis; Klaus Mohr
Journal:  Nat Commun       Date:  2012       Impact factor: 14.919
  9 in total

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