| Literature DB >> 25035836 |
Antongiulio Scarno1, Fabio Massimo Perrotta1, Francesca Cardini1, Alessia Carboni1, Gianmarco Annibali1, Ennio Lubrano1, Antonio Spadaro1.
Abstract
Rheumatoid arthritis is a chronic autoimmune inflammatory disease associated with increased cardiovascular risk and higher mortality in respect to general population. Beyond joint disease, inflammation is the major determinant of accelerated atherosclerosis observed in rheumatoid arthritis. We review the relationship between inflammation, atherosclerosis and cardiovascular risk in rheumatoid arthritis, focusing on the assessment of subclinical atherosclerosis by functional and morphological methods. These tools include flow mediated dilatation, carotid intima-media thickness, ankle/brachial index, coronary calcium content, pulse wave analysis and serum biomarker of subclinical atherosclerosis.Entities:
Keywords: Atherosclerosis; Flow mediated dilatiation; Inflammation; Intima-media thickness; Rheumatoid arthritis
Year: 2014 PMID: 25035836 PMCID: PMC4095026 DOI: 10.5312/wjo.v5.i3.328
Source DB: PubMed Journal: World J Orthop ISSN: 2218-5836