Literature DB >> 25035724

Man with altered mentation after trauma.

Landon A Jones1, Mathew J Sarsfield2.   

Abstract

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Mesh:

Year:  2014        PMID: 25035724      PMCID: PMC4100824          DOI: 10.5811/westjem.2014.1.20487

Source DB:  PubMed          Journal:  West J Emerg Med        ISSN: 1936-900X


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A 37 year-old male presented after an altercation in which he was dragged by a vehicle. The patient was intoxicated and asking repetitive questions. He demonstrated significant facial trauma—including frank bloody discharge from both ears and dental trauma. His vitals signs were as follows: Temperature 36.8 C; Blood pressure: 125/88; Heart rate: 90; Respiratory rate: 24; O2 sat: 100% room air. His portable chest x-ray can be seen below (Figure 1).
Figure 1

Chest radiograph demonstrating a widened upper mediastinum.

Secondary to his mechanism, intoxication, and chest radiograph results, he was sent for computed tomography (CT) imaging. Immediately post CT, his imaging was reviewed (Figure 2). Shortly thereafter, the patient’s altered mentation worsened and he acutely decompensated.
Figure 2

Computed tomography of the thorax with intravenous contrast demonstrates a large right ventricular air embolus.

DIAGNOSIS

Iatrogenic air embolism

Iatrogenic air embolism is a rare side-effect of invasive and surgical procedures. While rare, retrospective studies demonstrate mortality up to 23% and recent prospective literature demonstrates a 1-year mortality of 21%. Morbidity is higher.1–5 Iatrogenic air emboli can be either arterial or venous. Arterial gas emboli (AGE) can manifest as chest pain, transient ischemic attack, stroke, or shock.3,5–7 While most are asymptomatic, venous gas emboli (VGE) more commonly present as shortness of breath.5, 6 It is important, though, to recognize that VGE can readily convert to AGE via right-to-left shunting mechanisms such as pulmonary arterial-venous malformations and patent foramen ovale (PFO). A PFO is present in approximately 26–39% of the general population.8–11 Additionally, it is important to remember that iatrogenic air emboli can occur secondary to procedures that we often consider routine in the emergency department, i.e., central line placement or—like our patient—CT with intravenous contrast. In our case the patient acutely decompensated, was intubated, and received hyperbaric oxygen therapy. After hyperbarics, the patient’s status improved and he was extubated in the intensive care unit and later discharged without complications.
  10 in total

1.  Transmitral Doppler: a new transthoracic contrast method for patent foramen ovale detection and quantification.

Authors:  A J Kerr; T Buck; K Chia; C M Chow; E Fox; R A Levine; M H Picard
Journal:  J Am Coll Cardiol       Date:  2000-11-15       Impact factor: 24.094

Review 2.  Patent foramen ovale: current pathology, pathophysiology, and clinical status.

Authors:  Hidehiko Hara; Renu Virmani; Elena Ladich; Shannon Mackey-Bojack; Jack Titus; Mark Reisman; William Gray; Masato Nakamura; Michael Mooney; Anil Poulose; Robert S Schwartz
Journal:  J Am Coll Cardiol       Date:  2005-09-29       Impact factor: 24.094

3.  Iatrogenic systemic air embolism treated with hyperbaric oxygen therapy.

Authors:  T B Jørgensen; A M Sørensen; E C Jansen
Journal:  Acta Anaesthesiol Scand       Date:  2008-04       Impact factor: 2.105

4.  Long-term outcome of iatrogenic gas embolism.

Authors:  Jacques Bessereau; Nicolas Genotelle; Cendrine Chabbaut; Anne Huon; Alexis Tabah; Jérôme Aboab; Sylvie Chevret; Djillali Annane
Journal:  Intensive Care Med       Date:  2010-03-11       Impact factor: 17.440

5.  Incidence and size of patent foramen ovale during the first 10 decades of life: an autopsy study of 965 normal hearts.

Authors:  P T Hagen; D G Scholz; W D Edwards
Journal:  Mayo Clin Proc       Date:  1984-01       Impact factor: 7.616

6.  Cerebral air embolism resulting from invasive medical procedures. Treatment with hyperbaric oxygen.

Authors:  B P Murphy; F J Harford; F S Cramer
Journal:  Ann Surg       Date:  1985-02       Impact factor: 12.969

7.  Air embolism after intravenous injection of contrast material.

Authors:  S R Ie; M H Rozans; H M Szerlip
Journal:  South Med J       Date:  1999-09       Impact factor: 0.954

Review 8.  Patent foramen ovale: a review of associated conditions and the impact of physiological size.

Authors:  E K Kerut; W T Norfleet; G D Plotnick; T D Giles
Journal:  J Am Coll Cardiol       Date:  2001-09       Impact factor: 24.094

9.  Iatrogenic cerebral air embolism: importance of an early hyperbaric oxygenation.

Authors:  P Blanc; A Boussuges; K Henriette; J M Sainty; M Deleflie
Journal:  Intensive Care Med       Date:  2002-03-21       Impact factor: 17.440

10.  Paradoxical air embolism successfully treated with hyperbaric oxygen.

Authors:  Jesse E Scruggs; Aaron Joffe; Kenneth E Wood
Journal:  J Intensive Care Med       Date:  2008 May-Jun       Impact factor: 3.510

  10 in total

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