Literature DB >> 25033172

MicroRNA-mediated repression combats depression.

Mary P Heyer1, Paul J Kenny2.   

Abstract

Precisely how SSRIs induce long-term modifications in serotonin transmission to elicit their antidepressant actions is unclear. In this issue of Neuron, Issler et al. (2014) identify a key role for microRNA-135a [corrected] in the raphe nuclei in the molecular mechanisms underlying the therapeutic actions of SSRIs.
Copyright © 2014 Elsevier Inc. All rights reserved.

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Year:  2014        PMID: 25033172     DOI: 10.1016/j.neuron.2014.07.008

Source DB:  PubMed          Journal:  Neuron        ISSN: 0896-6273            Impact factor:   17.173


  3 in total

1.  miR-16 and Fluoxetine Both Reverse Autophagic and Apoptotic Change in Chronic Unpredictable Mild Stress Model Rats.

Authors:  Yang Yang; Zhiying Hu; Xiaoxue Du; Henry Davies; Xue Huo; Marong Fang
Journal:  Front Neurosci       Date:  2017-07-25       Impact factor: 4.677

Review 2.  Epigenetic Modifications of Major Depressive Disorder.

Authors:  Kathleen Saavedra; Ana María Molina-Márquez; Nicolás Saavedra; Tomás Zambrano; Luis A Salazar
Journal:  Int J Mol Sci       Date:  2016-08-05       Impact factor: 5.923

3.  Serum-based microRNA biomarkers for major depression: MiR-16, miR-135a, and miR-1202.

Authors:  Ali Gheysarzadeh; Nourkhoda Sadeghifard; Loghman Afraidooni; Farahnaz Pooyan; Mohammad Reza Mofid; Hassan Valadbeigi; Hadi Bakhtiari; Sattar Keikhavani
Journal:  J Res Med Sci       Date:  2018-08-23       Impact factor: 1.852

  3 in total

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