Philip J Wenger1, Fred Rottnek, Todd Parker, Jeffrey S Crippin. 1. Philip J. Wenger is with the Department of Pharmacy Practice, St. Louis College of Pharmacy, St. Louis, MO. Fred Rottnek is with the Department of Family & Community Medicine, Saint Louis University School of Medicine, St. Louis. Todd Parker is with the Saint Louis County Department of Health, Clayton, MO. Jeffrey S. Crippin is with the Department of Medicine, Washington University School of Medicine, St. Louis.
Abstract
OBJECTIVES: We sought to validate previous reports of HCV prevalence in jails, identify HCV risk factors prevalence, and identify risk factors associated with HCV infection in this population. METHODS: Inmates at the Buzz Westfall Justice Center (BWJC) in St. Louis, Missouri, were offered risk factor screening for HCV and anti-HCV antibody testing from December 2012 through May 2013. Demographic and risk factor information were assessed for significant associations with positive HCV antibody results. Risk factors that were significantly associated in univariate analysis were assessed using binary logistic regression to model the relationship between positive HCV results and the risk factors and demographics. RESULTS: Fifty of 304 inmates were positive for HCV, with a prevalence of 16.4%. The risk factors significantly associated with increased risk for positive HCV antibody were age (odds ratio [OR] = 1.09; 95% confidence interval [CI] = 1.04, 1.15 for each year), injection drug use (OR = 53.87; 95% CI = 17.78, 163.21), sex with HCV-positive partner (OR = 7.35; 95% CI = 1.41, 38.20), and tattoos by a nonlicensed provider (OR = 2.62; 95% CI = 1.09, 6.33). Prevalence for women was 3 times that of men (38% vs 12%). CONCLUSIONS: Prevalence of HCV at BWJC was similar to previous jail studies, which is lower than reported prison rates and higher than the general population.
OBJECTIVES: We sought to validate previous reports of HCV prevalence in jails, identify HCV risk factors prevalence, and identify risk factors associated with HCV infection in this population. METHODS: Inmates at the Buzz Westfall Justice Center (BWJC) in St. Louis, Missouri, were offered risk factor screening for HCV and anti-HCV antibody testing from December 2012 through May 2013. Demographic and risk factor information were assessed for significant associations with positive HCV antibody results. Risk factors that were significantly associated in univariate analysis were assessed using binary logistic regression to model the relationship between positive HCV results and the risk factors and demographics. RESULTS: Fifty of 304 inmates were positive for HCV, with a prevalence of 16.4%. The risk factors significantly associated with increased risk for positive HCV antibody were age (odds ratio [OR] = 1.09; 95% confidence interval [CI] = 1.04, 1.15 for each year), injection drug use (OR = 53.87; 95% CI = 17.78, 163.21), sex with HCV-positive partner (OR = 7.35; 95% CI = 1.41, 38.20), and tattoos by a nonlicensed provider (OR = 2.62; 95% CI = 1.09, 6.33). Prevalence for women was 3 times that of men (38% vs 12%). CONCLUSIONS: Prevalence of HCV at BWJC was similar to previous jail studies, which is lower than reported prison rates and higher than the general population.
Authors: M J Alter; D Kruszon-Moran; O V Nainan; G M McQuillan; F Gao; L A Moyer; R A Kaslow; H S Margolis Journal: N Engl J Med Date: 1999-08-19 Impact factor: 91.245
Authors: Bryce D Smith; Rebecca L Morgan; Geoff A Beckett; Yngve Falck-Ytter; Deborah Holtzman; Chong-Gee Teo; Amy Jewett; Brittney Baack; David B Rein; Nita Patel; Miriam Alter; Anthony Yartel; John W Ward Journal: MMWR Recomm Rep Date: 2012-08-17
Authors: Adrian M Di Bisceglie; Andre C Lyra; Myron Schwartz; Rajender K Reddy; Paul Martin; Gregory Gores; Anna S F Lok; Khozema B Hussain; Robert Gish; David H Van Thiel; Zobair Younossi; Myron Tong; Tarek Hassanein; Luis Balart; Jacquelyn Fleckenstein; Stephen Flamm; Andres Blei; Alex S Befeler Journal: Am J Gastroenterol Date: 2003-09 Impact factor: 10.864
Authors: Kathleen N Ly; Jian Xing; R Monina Klevens; Ruth B Jiles; John W Ward; Scott D Holmberg Journal: Ann Intern Med Date: 2012-02-21 Impact factor: 25.391
Authors: Karen A Hennessey; Andrea A Kim; Vivian Griffin; Nicoline T Collins; Cindy M Weinbaum; Keith Sabin Journal: J Urban Health Date: 2008-07-12 Impact factor: 3.671
Authors: Matthew J Akiyama; Fatos Kaba; Zachary Rosner; Howard Alper; Aimee Kopolow; Alain H Litwin; Homer Venters; Ross MacDonald Journal: Public Health Rep Date: 2016-12-14 Impact factor: 2.792
Authors: Giuseppe Scelza; Alessandra Amato; Antonio Maria Pagano; Giuseppe De Matteis; Rosa Caruso; Antonio Scelza; Laura Sisalli; Sebastiana De Biasi; Francesca Marigliano; Mario Gagliardi; Stefano Martina; Alfredo Iandolo Journal: Ann Gastroenterol Date: 2021-11-10