Literature DB >> 25032104

Intra-abdominal desmoid tumor after liver transplantation: A case report.

Vidya A Fleetwood1, Shannon Zielsdorf1, Sheila Eswaran1, Shriram Jakate1, Edie Y Chan1.   

Abstract

We are reporting the first documented case of an abdominal desmoid tumor presenting primarily after liver transplantation. This tumor, well described in the literature as occurring both in conjunction with familial adenomatous polyposis as well as in the post-surgical patient, has never been noted after solid organ transplantation and was therefore not included in our differential upon presentation. Definitive diagnosis required the patient to undergo surgical excision and immunochemical staining of the mass for confirmation. A review of the literature showed no primary tumors after transplantation. In a population of patients who received a small bowel transplant after they developed short gut post radical resection of aggressive fibromatosis, only rare recurrences were seen. No connection of tumor development with immunosuppression or need to decrease immunosuppressant treatment has been demonstrated in these patients. Our case and the literature show the risk of this tumor presenting in the post-transplantation patient and the need for a high index of suspicion in patients who present with a complex mass after transplantation to prevent progression of the disease beyond a resectable lesion. Results of a thorough search of the literature are detailed and the medical and surgical management of both resectable and unresectable lesions is reviewed.

Entities:  

Keywords:  Desmoid; Immunosuppression; Intra-abdominal fibromatosis; Liver transplantation; Recurrence; Solid organ transplantation

Year:  2014        PMID: 25032104      PMCID: PMC4094950          DOI: 10.5500/wjt.v4.i2.148

Source DB:  PubMed          Journal:  World J Transplant        ISSN: 2220-3230


  14 in total

Review 1.  A to Z of desmoid tumors.

Authors:  Atul B Shinagare; Nikhil H Ramaiya; Jyothi P Jagannathan; Katherine M Krajewski; Angela A Giardino; James E Butrynski; Chandrajit P Raut
Journal:  AJR Am J Roentgenol       Date:  2011-12       Impact factor: 3.959

2.  Intestinal transplantation for the treatment of neoplastic disease.

Authors:  Jang I Moon; Gennaro Selvaggi; Seigo Nishida; David M Levi; Tomoaki Kato; Philip Ruiz; Pablo Bejarano; Juan R Madariaga; Andreas G Tzakis
Journal:  J Surg Oncol       Date:  2005-12-15       Impact factor: 3.454

3.  Imatinib for progressive and recurrent aggressive fibromatosis (desmoid tumors): an FNCLCC/French Sarcoma Group phase II trial with a long-term follow-up.

Authors:  N Penel; A Le Cesne; B N Bui; D Perol; E G Brain; I Ray-Coquard; C Guillemet; C Chevreau; D Cupissol; S Chabaud; M Jimenez; F Duffaud; S Piperno-Neumann; L Mignot; J-Y Blay
Journal:  Ann Oncol       Date:  2010-07-09       Impact factor: 32.976

4.  The efficacy of radiotherapy as postoperative treatment for desmoid tumors.

Authors:  J A Jelinek; K J Stelzer; E Conrad; J Bruckner; M Kliot; W Koh; G E Laramore
Journal:  Int J Radiat Oncol Biol Phys       Date:  2001-05-01       Impact factor: 7.038

Review 5.  Surgery versus radiation therapy for patients with aggressive fibromatosis or desmoid tumors: A comparative review of 22 articles.

Authors:  J J Nuyttens; P F Rust; C R Thomas; A T Turrisi
Journal:  Cancer       Date:  2000-04-01       Impact factor: 6.860

Review 6.  Desmoid tumours.

Authors:  C J Shields; D C Winter; W O Kirwan; H P Redmond
Journal:  Eur J Surg Oncol       Date:  2001-12       Impact factor: 4.424

Review 7.  Desmoid tumors: clinical features and treatment options for advanced disease.

Authors:  Bernd Kasper; Philipp Ströbel; Peter Hohenberger
Journal:  Oncologist       Date:  2011-04-08

8.  A critical analysis of treatment strategies in desmoid tumours: a review of a series of 106 cases.

Authors:  E Stoeckle; J M Coindre; M Longy; M Bui Nguyen Binh; G Kantor; M Kind; C Tunon de Lara; A Avril; F Bonichon; B Nguyen Bui
Journal:  Eur J Surg Oncol       Date:  2008-08-29       Impact factor: 4.424

9.  Extra-abdominal desmoid tumors: a report of 234 cases.

Authors:  Henry J Mankin; Francis J Hornicek; Dempsey S Springfield
Journal:  J Surg Oncol       Date:  2010-10-01       Impact factor: 3.454

Review 10.  The pharmacological treatment of aggressive fibromatosis: a systematic review.

Authors:  J Janinis; M Patriki; L Vini; G Aravantinos; J S Whelan
Journal:  Ann Oncol       Date:  2003-02       Impact factor: 32.976

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