| Literature DB >> 25031774 |
Ge Wen1, Meifang Li1, Lijun Xu2, Peiqian Hu1, Xin Liao3, Chuang Lin4, Liang Zhao5.
Abstract
Solitary fibrous tumors (SFTs) rarely occur in the central nervous system (CNS). Involvement of the brainstem and pineal gland is rarely recorded. Herein, we represent 2 cases of SFTs and firstly report SFT of the pineal gland. Cranial MR imaging showed isointense to hypointense signal intensity, and marked enhancement. Microscopically, the tumors showed characteristic "patternless-pattern" architecture. Elongated tumour cells formed fascicles alternating with hypocellular densely collagenous stroma. Immunohistochemistry for CD34, BCL2, and CD99 favors the definitive diagnosis of SFT. It is difficult to predict prognosis in patients with intraventricular SFT. In general, complete surgical resection may offer the best chance of a favorable clinical outcome.Entities:
Keywords: CD34; Solitary fibrous tumor; central nervous system; immunohistochemistry; magnetic resonance imaging
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Year: 2014 PMID: 25031774 PMCID: PMC4097254
Source DB: PubMed Journal: Int J Clin Exp Pathol ISSN: 1936-2625