Literature DB >> 25031697

Effect of Nrf2 on rat ovarian tissues against atrazine-induced anti-oxidative response.

Fan Zhao1, Kun Li2, Lijing Zhao3, Jian Liu4, Qi Suo4, Jing Zhao3, Hebin Wang3, Shuhua Zhao4.   

Abstract

The environmental persistence and bioaccumulation of herbicide atrazine may pose a significant threat to human health. In this experiment, Wistar rats were treated by 5, 25 and 125 mg·kg(-1) atrazine respectively for 28 days, and the oxidative stress responses as well as the activations of Nrf2 signaling pathway in ovarian tissues induced by atrazine were observed. The results showed that after be treated by atrazine, the proportion of atretic follicles in the rat ovary were increased, the contents of NO and MDA in the tissue homogenates were increased, the over-expressed Nrf2 transferred into the nuclei and played an antioxidant role by up-regulated the expression of II phase detoxifying enzymes such as HO1 and NQO1 and the expression of antioxidant enzymes such as CAT, SOD and GSH-PX.

Entities:  

Keywords:  Atrazine; Nrf2 signal pathway; ovarian tissues; oxidative stress; rat

Mesh：

Substances：

Year:  2014        PMID： 25031697      PMCID： PMC4097279     

Source DB:  PubMed          Journal:  Int J Clin Exp Pathol        ISSN： 1936-2625


  38 in total

1.  The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase.

Authors:  Sara B Cullinan; John D Gordan; Jianping Jin; J Wade Harper; J Alan Diehl
Journal:  Mol Cell Biol       Date:  2004-10       Impact factor: 4.272

Review 2.  Unique function of the Nrf2-Keap1 pathway in the inducible expression of antioxidant and detoxifying enzymes.

Authors:  Akira Kobayashi; Tsutomu Ohta; Masayuki Yamamoto
Journal:  Methods Enzymol       Date:  2004       Impact factor: 1.600

3.  The biology of oxygen radicals.

Authors:  I Fridovich
Journal:  Science       Date:  1978-09-08       Impact factor: 47.728

4.  Molecular cloning and functional characterization of a new Cap'n' collar family transcription factor Nrf3.

Authors:  A Kobayashi; E Ito; T Toki; K Kogame; S Takahashi; K Igarashi; N Hayashi; M Yamamoto
Journal:  J Biol Chem       Date:  1999-03-05       Impact factor: 5.157

5.  Small Maf proteins interact with the human transcription factor TCF11/Nrf1/LCR-F1.

Authors:  O Johnsen; N Skammelsrud; L Luna; M Nishizawa; H Prydz; A B Kolstø
Journal:  Nucleic Acids Res       Date:  1996-11-01       Impact factor: 16.971

6.  A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

Authors:  M M Bradford
Journal:  Anal Biochem       Date:  1976-05-07       Impact factor: 3.365

7.  Developmental atrazine exposure suppresses immune function in male, but not female Sprague-Dawley rats.

Authors:  Andrew A Rooney; Raymond A Matulka; Robert W Luebke
Journal:  Toxicol Sci       Date:  2003-09-26       Impact factor: 4.849

Review 8.  A strategy for cancer prevention: stimulation of the Nrf2-ARE signaling pathway.

Authors:  Yuesheng Zhang; Gary B Gordon
Journal:  Mol Cancer Ther       Date:  2004-07       Impact factor: 6.261

9.  Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers.

Authors:  Nobunao Wakabayashi; Albena T Dinkova-Kostova; W David Holtzclaw; Moon-Il Kang; Akira Kobayashi; Masayuki Yamamoto; Thomas W Kensler; Paul Talalay
Journal:  Proc Natl Acad Sci U S A       Date:  2004-02-05       Impact factor: 11.205

10.  Low-dose agrochemicals and lawn-care pesticides induce developmental toxicity in murine preimplantation embryos.

Authors:  Anne R Greenlee; Tammy M Ellis; Richard L Berg
Journal:  Environ Health Perspect       Date:  2004-05       Impact factor: 9.031
View more
  9 in total

1.  Lycopene ameliorates atrazine-induced oxidative damage in adrenal cortex of male rats by activation of the Nrf2/HO-1 pathway.

Authors:  Marwa Ahmed Abass; Shereen Ahmed Elkhateeb; Samia Adel Abd El-Baset; Asmaa Alhosiny Kattaia; Eman Mosallam Mohamed; Hebatallah Husseini Atteia
Journal:  Environ Sci Pollut Res Int       Date:  2016-04-22       Impact factor: 4.223

2.  A longitudinal study of atrazine and 2,4-D exposure and oxidative stress markers among iowa corn farmers.

Authors:  Catherine C Lerro; Laura E Beane Freeman; Lützen Portengen; Daehee Kang; Kyoungho Lee; Aaron Blair; Charles F Lynch; Berit Bakke; Anneclaire J De Roos; Roel C H Vermeulen
Journal:  Environ Mol Mutagen       Date:  2017-01       Impact factor: 3.216

3.  Heme oxygenase 1 plays role of neuron-protection by regulating Nrf2-ARE signaling post intracerebral hemorrhage.

Authors:  Xiao-Ping Yin; Dan Wu; Jun Zhou; Zhi-Ying Chen; Bing Bao; Liang Xie
Journal:  Int J Clin Exp Pathol       Date:  2015-09-01

4.  Effects of that ATRA inhibits Nrf2-ARE pathway on glial cells activation after intracerebral hemorrhage.

Authors:  Xiao-Ping Yin; Jun Zhou; Dan Wu; Zhi-Ying Chen; Bing Bao
Journal:  Int J Clin Exp Pathol       Date:  2015-09-01

5.  A novel mechanism underlies atrazine toxicity in quails (Coturnix Coturnix coturnix): triggering ionic disorder via disruption of ATPases.

Authors:  Jia Lin; Hui-Xin Li; Lei Qin; Zheng-Hai Du; Jun Xia; Jin-Long Li
Journal:  Oncotarget       Date:  2016-12-20

6.  Expression and localization of nuclear factor erythroid 2-related factor 2 in the ovarian tissues of mice at different ages.

Authors:  Namita Sindan; Adheesh Bhandari; Yu Zhao; Xiaosheng Lu; Jieqiang Lv
Journal:  Exp Ther Med       Date:  2018-08-14       Impact factor: 2.447

7.  Effects of Glycyrrhiza polysaccharide in diet on growth performance, serum antioxidant capacity, and biochemistry of broilers.

Authors:  C Zhang; C X Li; Q Shao; W B Chen; L Ma; W H Xu; Y X Li; S C Huang; Y B Ma
Journal:  Poult Sci       Date:  2020-12-13       Impact factor: 3.352

8.  Protective Effects of Pterostilbene on Lipopolysaccharide-Induced Acute Lung Injury in Mice by Inhibiting NF-κB and Activating Nrf2/HO-1 Signaling Pathways.

Authors:  Yong Zhang; Zhen Han; Aimin Jiang; Di Wu; Shuangqiu Li; Ziyi Liu; Zhengkai Wei; Zhengtao Yang; Changming Guo
Journal:  Front Pharmacol       Date:  2021-01-29       Impact factor: 5.810

9.  The Protective Effect of Sulforaphane against Oxidative Stress through Activation of NRF2/ARE Pathway in Human Granulosa Cells.

Authors:  Sahar Esfandyari; Ashraf Aleyasin; Zahra Noroozi; Maryam Taheri; Mahshad Khodarahmian; Mojtaba Eslami; Zahra Rashidi; Fardin Amidi
Journal:  Cell J       Date:  2021-11-23       Impact factor: 2.479
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.