| Literature DB >> 25031271 |
Sangeeta N Bhatia1, Gregory H Underhill2, Kenneth S Zaret3, Ira J Fox4.
Abstract
Despite the tremendous hurdles presented by the complexity of the liver's structure and function, advances in liver physiology, stem cell biology and reprogramming, and the engineering of tissues and devices are accelerating the development of cell-based therapies for treating liver disease and liver failure. This State of the Art Review discusses both the near- and long-term prospects for such cell-based therapies and the unique challenges for clinical translation.Entities:
Mesh:
Year: 2014 PMID: 25031271 PMCID: PMC4374645 DOI: 10.1126/scitranslmed.3005975
Source DB: PubMed Journal: Sci Transl Med ISSN: 1946-6234 Impact factor: 17.956