Literature DB >> 25030921

Targeted genome modification via triple helix formation.

Adele S Ricciardi1, Nicole A McNeer, Kavitha K Anandalingam, W Mark Saltzman, Peter M Glazer.   

Abstract

Triplex-forming oligonucleotides (TFOs) are capable of coordinating genome modification in a targeted, site-specific manner, causing mutagenesis or even coordinating homologous recombination events. Here, we describe the use of TFOs such as peptide nucleic acids for targeted genome modification. We discuss this method and its applications and describe protocols for TFO design, delivery, and evaluation of activity in vitro and in vivo.

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Year:  2014        PMID： 25030921      PMCID： PMC5111905          DOI： 10.1007/978-1-4939-0992-6_8

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  57 in total

1.  Sequence-specific photo-induced cross-linking of the two strands of double-helical DNA by a psoralen covalently linked to a triple helix-forming oligonucleotide.

Authors:  M Takasugi; A Guendouz; M Chassignol; J L Decout; J Lhomme; N T Thuong; C Hélène
Journal:  Proc Natl Acad Sci U S A       Date:  1991-07-01       Impact factor: 11.205

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Journal:  Proc Natl Acad Sci U S A       Date:  1953-02       Impact factor: 11.205

3.  Triplex-mediated gene modification.

Authors:  Erica B Schleifman; Joanna Y Chin; Peter M Glazer
Journal:  Methods Mol Biol       Date:  2008

4.  Mutagenesis in mammalian cells induced by triple helix formation and transcription-coupled repair.

Authors:  G Wang; M M Seidman; P M Glazer
Journal:  Science       Date:  1996-02-09       Impact factor: 47.728

5.  Controlled DNA delivery systems.

Authors:  D Luo; K Woodrow-Mumford; N Belcheva; W M Saltzman
Journal:  Pharm Res       Date:  1999-08       Impact factor: 4.200

6.  Surface modification of biodegradable polyesters with fatty acid conjugates for improved drug targeting.

Authors:  Tarek M Fahmy; Robert M Samstein; Casey C Harness; W Mark Saltzman
Journal:  Biomaterials       Date:  2005-04-18       Impact factor: 12.479

7.  Strand invasion of mixed-sequence, double-helical B-DNA by γ-peptide nucleic acids containing G-clamp nucleobases under physiological conditions.

Authors:  Srinivas Rapireddy; Raman Bahal; Danith H Ly
Journal:  Biochemistry       Date:  2011-04-25       Impact factor: 3.162

8.  Distance and affinity dependence of triplex-induced recombination.

Authors:  Melissa P Knauert; Janice A Lloyd; Faye A Rogers; Hirock J Datta; Michael L Bennett; Daniel L Weeks; Peter M Glazer
Journal:  Biochemistry       Date:  2005-03-15       Impact factor: 3.162

9.  Efficient pH-independent sequence-specific DNA binding by pseudoisocytosine-containing bis-PNA.

Authors:  M Egholm; L Christensen; K L Dueholm; O Buchardt; J Coull; P E Nielsen
Journal:  Nucleic Acids Res       Date:  1995-01-25       Impact factor: 16.971

10.  Targeted correction of a thalassemia-associated beta-globin mutation induced by pseudo-complementary peptide nucleic acids.

Authors:  Pallavi Lonkar; Ki-Hyun Kim; Jean Y Kuan; Joanna Y Chin; Faye A Rogers; Melissa P Knauert; Ryszard Kole; Peter E Nielsen; Peter M Glazer
Journal:  Nucleic Acids Res       Date:  2009-04-13       Impact factor: 16.971
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  6 in total

Review 1.  Liver-targeted gene therapy: Approaches and challenges.

Authors:  Rajagopal N Aravalli; John D Belcher; Clifford J Steer
Journal:  Liver Transpl       Date:  2015-06       Impact factor: 6.112

Review 2.  Therapeutic Peptide Nucleic Acids: Principles, Limitations, and Opportunities.

Authors:  Elias Quijano; Raman Bahal; Adele Ricciardi; W Mark Saltzman; Peter M Glazer
Journal:  Yale J Biol Med       Date:  2017-12-19

Review 3.  Peptide Nucleic Acids as a Tool for Site-Specific Gene Editing.

Authors:  Adele S Ricciardi; Elias Quijano; Rachael Putman; W Mark Saltzman; Peter M Glazer
Journal:  Molecules       Date:  2018-03-11       Impact factor: 4.927

4.  In utero nanoparticle delivery for site-specific genome editing.

Authors:  Adele S Ricciardi; Raman Bahal; James S Farrelly; Elias Quijano; Anthony H Bianchi; Valerie L Luks; Rachael Putman; Francesc López-Giráldez; Süleyman Coşkun; Eric Song; Yanfeng Liu; Wei-Che Hsieh; Danith H Ly; David H Stitelman; Peter M Glazer; W Mark Saltzman
Journal:  Nat Commun       Date:  2018-06-26       Impact factor: 17.694

5.  Surface conjugation of antibodies improves nanoparticle uptake in bronchial epithelial cells.

Authors:  Valerie L Luks; Hanna Mandl; Jenna DiRito; Christina Barone; Mollie R Freedman-Weiss; Adele S Ricciardi; Gregory G Tietjen; Marie E Egan; W Mark Saltzman; David H Stitelman
Journal:  PLoS One       Date:  2022-04-06       Impact factor: 3.752

Review 6.  Using Gene Editing Approaches to Fine-Tune the Immune System.

Authors:  Kristina Pavlovic; María Tristán-Manzano; Noelia Maldonado-Pérez; Marina Cortijo-Gutierrez; Sabina Sánchez-Hernández; Pedro Justicia-Lirio; M Dolores Carmona; Concha Herrera; Francisco Martin; Karim Benabdellah
Journal:  Front Immunol       Date:  2020-09-29       Impact factor: 7.561
  6 in total

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