| Literature DB >> 25029630 |
A P Hopper1, J M Dugan, A A Gill, O J L Fox, P W May, J W Haycock, F Claeyssens.
Abstract
In this study, we report the production of amine functionalized nanodiamond. The amine functionalized nanodiamond forms a conformal monolayer on a negatively charged surface produced via plasma polymerization of acrylic acid. Nanodiamond terminated surfaces were studied as substrates for neuronal cell culture. NG108-15 neuroblastoma-glioma hybrid cells were successfully cultured upon amine functionalized nanodiamond coated surfaces for between 1 and 7 d. Additionally, primary dorsal root ganglion (DRG) neurons and Schwann cells isolated from Wistar rats were also successfully cultured over a period of 21 d illustrating the potential of the coating for applications in the treatment of peripheral nerve injury.Entities:
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Year: 2014 PMID： 25029630 DOI： 10.1088/1748-6041/9/4/045009
Source DB: PubMed Journal: Biomed Mater ISSN： 1748-6041 Impact factor: 3.715