Literature DB >> 25027654

Apoptosis. DR5 unfolds ER stress.

Eytan Zlotorynski.   

Abstract

ER stress induces apoptosis through DR5, which is regulated by the UPR factors PERK and IRE1α.

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Year:  2014        PMID: 25027654     DOI: 10.1038/nrm3843

Source DB:  PubMed          Journal:  Nat Rev Mol Cell Biol        ISSN: 1471-0072            Impact factor:   94.444


  2 in total

Review 1.  The unfolded protein response: controlling cell fate decisions under ER stress and beyond.

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Journal:  Nat Rev Mol Cell Biol       Date:  2012-01-18       Impact factor: 94.444

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  2 in total
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2.  RUNX3 enhances TRAIL-induced apoptosis by upregulating DR5 in colorectal cancer.

Authors:  Bo Ram Kim; Seong Hye Park; Yoon A Jeong; Yoo Jin Na; Jung Lim Kim; Min Jee Jo; Soyeon Jeong; Hye Kyeong Yun; Sang Cheul Oh; Dae-Hee Lee
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4.  AF8c, a Multi-Kinase Inhibitor Induces Apoptosis by Activating DR5/Nrf2 via ROS in Colorectal Cancer Cells.

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5.  Plumbagin suppresses epithelial to mesenchymal transition and stemness via inhibiting Nrf2-mediated signaling pathway in human tongue squamous cell carcinoma cells.

Authors:  Shu-Ting Pan; Yiru Qin; Zhi-Wei Zhou; Zhi-Xu He; Xueji Zhang; Tianxin Yang; Yin-Xue Yang; Dong Wang; Shu-Feng Zhou; Jia-Xuan Qiu
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  5 in total

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