Literature DB >> 25027278

Assessment of spatial uncertainty in computed tomography-based Gamma Knife stereotactic radiosurgery process with automated positioning system.

Hisato Nakazawa1, Masataka Komori, Hiroshi Oguchi, Yuta Shibamoto, Takahiko Tsugawa, Yukio Uchiyama, Tatsuya Kobayashi.   

Abstract

BACKGROUND: In this study, we assessed the geometric accuracy of an automated positioning system in Gamma Knife (GK) surgery. Specifically, we looked at the total spatial uncertainty over the entire treatment range of GK stereotactic radiosurgery (SRS) procedures in both the GK model C and the Perfexion (PFX).
METHODS: An originally-developed phantom and a radiochromic film were used for obtaining actual dose distributions. The phantom, with inserted films on different axial planes (z = 60, 75, 100, 125, 140 mm), sagittal planes (x = 60, 75, 100, 125, 140 mm), and coronal planes (y = 60, 75, 100, 125, 140 mm), was placed on a Leksell skull frame. Computed tomography (CT) was then performed with a stereotactic localizer box attached to the frame, and dose planning was made using the Leksell GammaPlan treatment planning system. The phantom finally received beam delivery using a single shot of a 4-mm collimator helmet. The discrepancy between the planned shot position and the irradiated center position was evaluated by a dedicated film analysis software.
RESULTS: The total uncertainty of CT-based GK SRS was less than 1 mm for almost all measured points over the stereotactic space in both the model C and the PFX. In addition, the geometric accuracy of the automated positioning system was estimated to be less than 0.1 mm and equal to 0.5 mm in the central and peripheral areas, respectively.
CONCLUSIONS: We confirmed that the total spatial uncertainties of both the GK model C and the PFX are acceptable for clinical use.

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Year:  2014        PMID: 25027278     DOI: 10.1007/s00701-014-2178-6

Source DB:  PubMed          Journal:  Acta Neurochir (Wien)        ISSN: 0001-6268            Impact factor:   2.216


  3 in total

1.  Stereotactic radiosurgery of glomus jugulare tumors: current concepts, recent advances and future perspectives.

Authors:  Omer Sager; Ferrat Dincoglan; Murat Beyzadeoglu
Journal:  CNS Oncol       Date:  2015

2.  Total workflow uncertainty of frameless radiosurgery with the Gamma Knife Icon cone-beam computed tomography.

Authors:  William N Duggar; Bart Morris; Rui He; Claus Yang
Journal:  J Appl Clin Med Phys       Date:  2022-02-14       Impact factor: 2.243

3.  Gamma Knife® icon CBCT offers improved localization workflow for frame-based treatment.

Authors:  William N Duggar; Bart Morris; Ali Fatemi; Jemeria Bonds; Rui He; Madhava Kanakamedala; Roberto Rey-Dios; Srinivasan Vijayakumar; Claus Yang
Journal:  J Appl Clin Med Phys       Date:  2019-10-06       Impact factor: 2.102

  3 in total

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