Literature DB >> 2502507

Exclusive radiation therapy: the treatment of early tonsillar tumors.

A Lusinchi1, P Wibault, P Marandas, I Kunkler, F Eschwege.   

Abstract

One hundred and ninety-three T1 or T2 tumors of the tonsillar region have been treated by exclusive external irradiation between 1970 and 1982. Seventy-five percent of these tumors were classified as T2. There was no relationship between T and N stages. The nodal involvement was essentially linked to the macroscopic appearance of the tumor (superficial or nodular) and to the histology. The 5-year survival rate of the whole population was 58%. N stage and macroscopic appearance only influenced the survival. The local control was 88% for T1, 79% for T2. The main prognostic factors for local control were the histological type, with a 93% local control rate for poorly differentiated tumors versus 73% for well differentiated ones, and the macroscopic appearance, with a 83% local control rate for nodular tumors versus 75% for superficial ones. Superficial tumors spreading forward the anterior pilar have a higher local failure rate. All the patients' charts have been reviewed, and we observed a high percentage of marginal recurrences. The technique of irradiation, above all in case of a superficial tumor, must take into account the possibility of "geographic miss" and keep large safety margins.

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Year:  1989        PMID: 2502507     DOI: 10.1016/0360-3016(89)90439-2

Source DB:  PubMed          Journal:  Int J Radiat Oncol Biol Phys        ISSN: 0360-3016            Impact factor:   7.038


  3 in total

1.  Radiotherapy alone or combined with chemotherapy as definitive treatment for squamous cell carcinoma of the tonsil.

Authors:  William R Kennedy; Michael P Herman; Rohan L Deraniyagala; Robert J Amdur; John W Werning; Peter Dziegielewski; Jessica Kirwan; Christopher G Morris; William M Mendenhall
Journal:  Eur Arch Otorhinolaryngol       Date:  2016-04-08       Impact factor: 2.503

2.  T1-T2 NO oropharyngeal cancers treated with surgery alone. A GETTEC study.

Authors:  Alain Cosmidis; Jean-Pierre Rame; Olivier Dassonville; Stéphane Temam; François Massip; Gilles Poissonnet; Marc Poupart; Patrick Marandas; Dominique De Raucourt
Journal:  Eur Arch Otorhinolaryngol       Date:  2003-10-09       Impact factor: 2.503

3.  Additional parameters to improve the prognostic value of the 8th edition of the UICC classification for human papillomavirus-related oropharyngeal tumors.

Authors:  Jos M J A A Straetmans; Marijn Stuut; Martin Lacko; Frank Hoebers; Ernst-Jan M Speel; Bernd Kremer
Journal:  Head Neck       Date:  2022-05-17       Impact factor: 3.821

  3 in total

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