Literature DB >> 25024662

Resolution of severe obstructive sleep apnea after treatment of anti-muscle kinase receptor-positive myasthenia gravis despite 60-pound weight gain.

Michael Morgenstern1, Effie Singas1, Bashar Zleik1, Harly Greenberg1.   

Abstract

Obstructive sleep apnea (OSA) in patients with myasthenia gravis (MG) may be caused by reduced pharyngeal dilator muscle activity. We report a patient with anti-muscle kinase receptor MG with severe OSA and hypoventilation that resolved upon successful treatment of MG despite a 60-lb weight gain.

Entities:  

Keywords:  anti-musk antibody; hypoventilation; myasthenia gravis; obstructive sleep apnea

Mesh：

Substances：

Year:  2014        PMID： 25024662      PMCID： PMC4067448          DOI： 10.5664/jcsm.3884

Source DB:  PubMed          Journal:  J Clin Sleep Med        ISSN： 1550-9389            Impact factor:   4.062


  4 in total

1.  Sleep apnea in patients with myasthenia gravis.

Authors:  M W Nicolle; S Rask; W J Koopman; C F P George; J Adams; S Wiebe
Journal:  Neurology       Date:  2006-07-11       Impact factor: 9.910

Review 2.  Update on muscle-specific tyrosine kinase antibody positive myasthenia gravis.

Authors:  Jeffrey T Guptill; Donald B Sanders
Journal:  Curr Opin Neurol       Date:  2010-10       Impact factor: 5.710

3.  Sleep disordered breathing in medically stable patients with myasthenia gravis.

Authors:  J Prudlo; J Koenig; S Ermert; J Juhász
Journal:  Eur J Neurol       Date:  2007-03       Impact factor: 6.089

4.  Sleep apnoea in well-controlled myasthenia gravis and the effect of thymectomy.

Authors:  A Amino; Z Shiozawa; T Nagasaka; K Shindo; K Ohashi; S Tsunoda; S Shintani
Journal:  J Neurol       Date:  1998-02       Impact factor: 4.849
  4 in total

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