Jan Magnus Fredheim1, J Røislien2, J Hjelmesæth3. 1. Morbid Obesity Center, Department of Medicine, Vestfold Hospital Trust, Tønsberg, Norway ; Department of Otolaryngology - Head and Neck Surgery, Vestfold Hospital Trust, Tønsberg, Norway ; Institute of Clinical Medicine, University of Oslo, Norway. 2. Morbid Obesity Center, Department of Medicine, Vestfold Hospital Trust, Tønsberg, Norway ; Department of Biostatistics, Institute of Basic Medical Sciences, University of Oslo, Norway. 3. Morbid Obesity Center, Department of Medicine, Vestfold Hospital Trust, Tønsberg, Norway ; Institute of Clinical Medicine, University of Oslo, Norway.
Abstract
STUDY OBJECTIVES: We aimed to validate the diagnostic accuracy and night-to-night variability of a simple 3-channel (type IV monitor) portable sleep monitor, ApneaLink (AL), in a population of morbidly obese subjects. DESIGN: Cross-sectional validation and diagnostic accuracy study. SETTING: Public tertiary care obesity center in Norway. PARTICIPANTS: A total of 105 (67 females) treatment seeking morbidly obese subjects were included, mean (SD) age 44.3 (11.4) years and BMI 43.6 (5.6) kg/m2. INTERVENTIONS: The patients underwent two successive nights of recordings; the first night with the AL only, and the following night with both the reference instrument Embletta (E), a type III portable somnograph, and the AL. MEASUREMENTS AND RESULTS: Main outcomes were diagnostic accuracy of AL as assessed by sensitivity, specificity and area under ROC curves, and level of agreement between AL and E. AL had high diagnostic accuracy at all levels of OSA, and the Bland-Altman plots showed good agreement between AL and E. The sensitivity and specificity of the instrument were 93% and 71% at the AHI cutoff 5 events/h, and 94% and 94% at the AHI cutoff 15, respectively. The night-to-night variability was low. CONCLUSION: Our results indicate that a simple 3-channel portable sleep monitor (ApneaLink) has a high diagnostic accuracy in diagnosing OSA in morbidly obese treatment seeking patients. Accordingly, this and similar instruments might help non-specialists to diagnose OSA in morbidly obese patients, and, importantly, help non-specialists to refer patients who need specific treatment to specialist without unnecessary delay.
STUDY OBJECTIVES: We aimed to validate the diagnostic accuracy and night-to-night variability of a simple 3-channel (type IV monitor) portable sleep monitor, ApneaLink (AL), in a population of morbidly obese subjects. DESIGN: Cross-sectional validation and diagnostic accuracy study. SETTING: Public tertiary care obesity center in Norway. PARTICIPANTS: A total of 105 (67 females) treatment seeking morbidly obese subjects were included, mean (SD) age 44.3 (11.4) years and BMI 43.6 (5.6) kg/m2. INTERVENTIONS: The patients underwent two successive nights of recordings; the first night with the AL only, and the following night with both the reference instrument Embletta (E), a type III portable somnograph, and the AL. MEASUREMENTS AND RESULTS: Main outcomes were diagnostic accuracy of AL as assessed by sensitivity, specificity and area under ROC curves, and level of agreement between AL and E. AL had high diagnostic accuracy at all levels of OSA, and the Bland-Altman plots showed good agreement between AL and E. The sensitivity and specificity of the instrument were 93% and 71% at the AHI cutoff 5 events/h, and 94% and 94% at the AHI cutoff 15, respectively. The night-to-night variability was low. CONCLUSION: Our results indicate that a simple 3-channel portable sleep monitor (ApneaLink) has a high diagnostic accuracy in diagnosing OSA in morbidly obese treatment seeking patients. Accordingly, this and similar instruments might help non-specialists to diagnose OSA in morbidly obesepatients, and, importantly, help non-specialists to refer patients who need specific treatment to specialist without unnecessary delay.
Authors: Susanna S S Ng; Tat-On Chan; Kin-Wang To; Jenny Ngai; Alvin Tung; Fanny W S Ko; David S C Hui Journal: Respirology Date: 2010-02 Impact factor: 6.424
Authors: Harald Hrubos-Strøm; Anna Randby; Silje K Namtvedt; Håvard A Kristiansen; Gunnar Einvik; Jūratėšaltytė Benth; Virend K Somers; Inger H Nordhus; Michael B Russell; Toril Dammen; Torbjørn Omland; Kari J Kværner Journal: J Sleep Res Date: 2011-03 Impact factor: 3.981
Authors: Leslie M Swanson; J Todd Arnedt; Mark R Rosekind; Gregory Belenky; Thomas J Balkin; Christopher Drake Journal: J Sleep Res Date: 2010-09-30 Impact factor: 3.981
Authors: Burcu Oktay; Thomas B Rice; Charles W Atwood; Michael Passero; Neeraj Gupta; Rachel Givelber; Oliver J Drumheller; Patricia Houck; Nancy Gordon; Patrick J Strollo Journal: J Clin Sleep Med Date: 2011-08-15 Impact factor: 4.062
Authors: Jan Magnus Fredheim; Jan Rollheim; Torbjørn Omland; Dag Hofsø; Jo Røislien; Kristian Vegsgaard; Jøran Hjelmesæth Journal: Cardiovasc Diabetol Date: 2011-09-25 Impact factor: 9.951
Authors: Kirk Kee; John Dixon; Jonathan Shaw; Elena Vulikh; Markus Schlaich; David M Kaye; Paul Zimmet; Matthew T Naughton Journal: J Clin Sleep Med Date: 2018-12-15 Impact factor: 4.062
Authors: Jennifer N Miller; Paula Schulz; Bunny Pozehl; Douglas Fiedler; Alissa Fial; Ann M Berger Journal: Sleep Breath Date: 2017-11-14 Impact factor: 2.816
Authors: Arthur Dawson; Richard T Loving; Robert M Gordon; Susan L Abel; Derek Loewy; Daniel F Kripke; Lawrence E Kline Journal: BMJ Open Date: 2015-06-30 Impact factor: 2.692