Literature DB >> 2502446

Arachidonic acid metabolism by perfused ram testis.

I Schön1, Y Sofer, M Cojacaru, S Grossman.   

Abstract

1. Arachidonic acid was metabolized by lipoxygenase and prostaglandin synthetase enzymes systems in the perfused ram testis. 2. The major product of the prostaglandin synthetase was 6-keto-PGF1 alpha (6KF). 3. Addition of testosterone resulted in a significant increase in the 6KF. 4. Arachidonic acid (AA) as well as testosterone penetrated the perfused testis. 5. Both 15-HPETE and 15-HETE, the products of the 15-lipoxygenase enzyme, were detected. 6. Addition of 0.1% BSA changed the pattern of the oxidized arachidonic acid metabolism.

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Year:  1989        PMID： 2502446     DOI： 10.1016/0020-711x(89)90021-9

Source DB:  PubMed          Journal:  Int J Biochem        ISSN： 0020-711X


  3 in total

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  3 in total

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