OBJECTIVE: Epidural electrocorticography (ECoG) activity may be more reliable and stable than single-unit-activity or local field potential. Invasive brain computer interface (BCI) devices are limited by mechanical mismatching and cellular reactive responses due to differences in the elastic modulus and the motion of stiff electrodes. We propose a mesh-shaped electrode to enhance the contactability between surface of dura and electrode. APPROACH: We designed a polyimide (PI) electrode with a mesh pattern for more conformal contact with a curved surface. We compared the contact capability of mesh PI electrodes with conventionally used sheet PI electrode. The electrical properties of the mesh PI electrode were evaluated for four weeks. We recorded the epidural ECoG (eECoG) activity on the surface of rhesus monkey brains while they performed a saccadic task for four months. MAIN RESULTS: The mesh PI electrode showed good contact with the agarose brain surface, as evaluated by visual inspection and signal measurement. It was about 87% accurate in predicting the direction of saccade eye movement. SIGNIFICANCE: Our results indicate that the mesh PI electrode was flexible and good contact on the curved surface and can record eECoG activity maintaining close contact to dura, which was proved by in vivo and in vitro test.
OBJECTIVE: Epidural electrocorticography (ECoG) activity may be more reliable and stable than single-unit-activity or local field potential. Invasive brain computer interface (BCI) devices are limited by mechanical mismatching and cellular reactive responses due to differences in the elastic modulus and the motion of stiff electrodes. We propose a mesh-shaped electrode to enhance the contactability between surface of dura and electrode. APPROACH: We designed a polyimide (PI) electrode with a mesh pattern for more conformal contact with a curved surface. We compared the contact capability of mesh PI electrodes with conventionally used sheet PI electrode. The electrical properties of the mesh PI electrode were evaluated for four weeks. We recorded the epidural ECoG (eECoG) activity on the surface of rhesus monkey brains while they performed a saccadic task for four months. MAIN RESULTS: The mesh PI electrode showed good contact with the agarose brain surface, as evaluated by visual inspection and signal measurement. It was about 87% accurate in predicting the direction of saccade eye movement. SIGNIFICANCE: Our results indicate that the mesh PI electrode was flexible and good contact on the curved surface and can record eECoG activity maintaining close contact to dura, which was proved by in vivo and in vitro test.
Authors: Amélie A Guex; Ariel Edward Hight; Shreya Narasimhan; Nicolas Vachicouras; Daniel J Lee; Stéphanie P Lacour; M Christian Brown Journal: Hear Res Date: 2019-02-26 Impact factor: 3.208
Authors: Virginia Woods; Michael Trumpis; Brinnae Bent; Kay Palopoli-Trojani; Chia-Han Chiang; Charles Wang; Chunxiu Yu; Michele N Insanally; Robert C Froemke; Jonathan Viventi Journal: J Neural Eng Date: 2018-09-24 Impact factor: 5.379
Authors: Jeyeon Lee; Hoseok Choi; Seho Lee; Baek Hwan Cho; Kyoung Ha Ahn; In Young Kim; Kyoung Min Lee; Dong Pyo Jang Journal: J Korean Med Sci Date: 2017-08 Impact factor: 2.153
Authors: Sam E John; Nicholas L Opie; Yan T Wong; Gil S Rind; Stephen M Ronayne; Giulia Gerboni; Sebastien H Bauquier; Terence J O'Brien; Clive N May; David B Grayden; Thomas J Oxley Journal: Sci Rep Date: 2018-05-30 Impact factor: 4.379