Literature DB >> 25024086

Access to novel functionalized trifluoromethyl β-lactams by ring expansion of aziridines.

S Decamps1, L Sevaille, S Ongeri, B Crousse.   

Abstract

From carboxylic acid trifluoromethyl aziridines, halogeno β-lactams were obtained stereoselectively by ring expansion. Different conditions such as radical, organometallic reactions allowed easy and selective access to CF3-β-lactams substituted at the C-3 position.

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Year:  2014        PMID： 25024086     DOI： 10.1039/c4ob01262c

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  2 in total

Review 1.  Synthetic Approaches toward Monocyclic 3-Amino-β-lactams.

Authors:  Sari Deketelaere; Tuyen Van Nguyen; Christian V Stevens; Matthias D'hooghe
Journal:  ChemistryOpen       Date:  2017-06-05       Impact factor: 2.911

2.  Direct Access to Substituted 4-CF3 β-Lactams at the C-3 Position.

Authors:  Monika Skibińska; Marcin Kaźmierczak; Thierry Milcent; Tomasz Cytlak; Henryk Koroniak; Benoit Crousse
Journal:  Front Chem       Date:  2019-08-06       Impact factor: 5.221
  2 in total

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