Literature DB >> 25023629

Cloning and characterization of a novel fructan 6-exohydrolase strongly inhibited by sucrose in Lolium perenne.

Jérémy Lothier1, André Van Laere, Marie-Pascale Prud'homme, Wim Van den Ende, Annette Morvan-Bertrand.   

Abstract

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CONCLUSION: The first 6-fructan exohydrolase (6-FEH) cDNA from Lolium perenne was cloned and characterized. Following defoliation, Lp6 - FEHa transcript level unexpectedly decreased together with an increase in total FEH activity. Lolium perenne is a major forage grass species that accumulates fructans, mainly composed of β(2,6)-linked fructose units. Fructans are mobilized through strongly increased activities of fructan exohydrolases (FEHs), sustaining regrowth following defoliation. To understand the complex regulation of fructan breakdown in defoliated grassland species, the objective was to clone and characterize new FEH genes in L. perenne. To find FEH genes related to refoliation, a defoliated tiller base cDNA library was screened. Characterization of the recombinant protein was performed in Pichia pastoris. In this report, the cloning and enzymatic characterization of the first 6-FEH from L. perenne is described. Following defoliation, during fructan breakdown, Lp6-FEHa transcript level unexpectedly decreased in elongating leaf bases (ELB) and in mature leaf sheaths (tiller base) in parallel to increased total FEH activities. In comparison, transcript levels of genes coding for fructosyltransferases (FTs) involved in fructan biosynthesis also decreased after defoliation but much faster than FEH transcript levels. Since Lp6-FEHa was strongly inhibited by sucrose, mechanisms modulating FEH activities are discussed. It is proposed that differences in the regulation of FEH activity among forage grasses influence their tolerance to defoliation.

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Year:  2014        PMID: 25023629     DOI: 10.1007/s00425-014-2110-6

Source DB:  PubMed          Journal:  Planta        ISSN: 0032-0935            Impact factor:   4.116


  45 in total

1.  Purification, cloning and functional characterization of a fructan 6-exohydrolase from wheat (Triticum aestivum L.).

Authors:  Liesbet Van Riet; Vinay Nagaraj; Wim Van den Ende; Stefan Clerens; Andres Wiemken; André Van Laere
Journal:  J Exp Bot       Date:  2005-12-05       Impact factor: 6.992

2.  Roles of the fructans from leaf sheaths and from the elongating leaf bases in the regrowth following defoliation of Lolium perenne L.

Authors:  A Morvan-Bertrand; J Boucaud; J Le Saos; M P Prud'homme
Journal:  Planta       Date:  2001-05       Impact factor: 4.116

3.  Molecular cloning and functional analysis of a novel 6&1-FEH from wheat (Triticum aestivum L.) preferentially degrading small graminans like bifurcose.

Authors:  Akira Kawakami; Midori Yoshida; Wim Van den Ende
Journal:  Gene       Date:  2005-09-26       Impact factor: 3.688

4.  Fructan 1-exohydrolases. beta-(2,1)-trimmers during graminan biosynthesis in stems of wheat? Purification, characterization, mass mapping, and cloning of two fructan 1-exohydrolase isoforms.

Authors:  Wim Van Den Ende; Stefan Clerens; Rudy Vergauwen; Liesbet Van Riet; André Van Laere; Midori Yoshida; Akira Kawakami
Journal:  Plant Physiol       Date:  2003-02       Impact factor: 8.340

5.  Metabolism of the Raffinose Family Oligosaccharides in Leaves of Ajuga reptans L. (Cold Acclimation, Translocation, and Sink to Source Transition: Discovery of Chain Elongation Enzyme).

Authors:  M. Bachmann; P. Matile; F. Keller
Journal:  Plant Physiol       Date:  1994-08       Impact factor: 8.340

6.  Water deficits in wheat: fructan exohydrolase (1-FEH) mRNA expression and relationship to soluble carbohydrate concentrations in two varieties.

Authors:  Jingjuan Zhang; Bernard Dell; Elisabeth Conocono; Irene Waters; Tim Setter; Rudi Appels
Journal:  New Phytol       Date:  2009-03       Impact factor: 10.151

Review 7.  Donor and acceptor substrate selectivity among plant glycoside hydrolase family 32 enzymes.

Authors:  Wim Van den Ende; Willem Lammens; André Van Laere; Lindsey Schroeven; Katrien Le Roy
Journal:  FEBS J       Date:  2009-09-17       Impact factor: 5.542

8.  Cloning, gene mapping, and functional analysis of a fructan 1-exohydrolase (1-FEH) from Lolium perenne implicated in fructan synthesis rather than in fructan mobilization.

Authors:  Jérémy Lothier; Bertrand Lasseur; Katrien Le Roy; André Van Laere; Marie-Pascale Prud'homme; Philippe Barre; Wim Van den Ende; Annette Morvan-Bertrand
Journal:  J Exp Bot       Date:  2007-04-24       Impact factor: 6.992

9.  Cloning and functional characterization of a fructan 1-exohydrolase (1-FEH) in the cold tolerant Patagonian species Bromus pictus.

Authors:  Florencia del Viso; Andrea F Puebla; H Esteban Hopp; Ruth Amelia Heinz
Journal:  Planta       Date:  2009-09-30       Impact factor: 4.116

10.  Influencing the binding configuration of sucrose in the active sites of chicory fructan 1-exohydrolase and sugar beet fructan 6-exohydrolase.

Authors:  Katrien Le Roy; Willem Lammens; André Van Laere; Wim Van den Ende
Journal:  New Phytol       Date:  2008-03-03       Impact factor: 10.151

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  12 in total

Review 1.  Interaction between fructan metabolism and plant growth regulators.

Authors:  Ruth E Márquez-López; Víctor M Loyola-Vargas; Patricia Araceli Santiago-García
Journal:  Planta       Date:  2022-01-27       Impact factor: 4.116

2.  Depletion of carbohydrate reserves limits nitrate uptake during early regrowth in Lolium perenne L.

Authors:  Qianqian Guo; Matthew Hamish Turnbull; Jiancheng Song; Jessica Roche; Ondrej Novak; Jana Späth; Paula Elizabeth Jameson; Jonathan Love
Journal:  J Exp Bot       Date:  2017-03-01       Impact factor: 6.992

3.  Chicory R2R3-MYB transcription factors CiMYB5 and CiMYB3 regulate fructan 1-exohydrolase expression in response to abiotic stress and hormonal cues.

Authors:  Hongbin Wei; Hongbo Zhao; Tao Su; Anja Bausewein; Steffen Greiner; Karsten Harms; Thomas Rausch
Journal:  J Exp Bot       Date:  2017-07-10       Impact factor: 6.992

4.  A Fructan Exohydrolase from Maize Degrades Both Inulin and Levan and Co-Exists with 1-Kestotriose in Maize.

Authors:  Silin Wu; Steffen Greiner; Chongjian Ma; Jiaxin Zhong; Xiaojia Huang; Thomas Rausch; Hongbo Zhao
Journal:  Int J Mol Sci       Date:  2021-05-13       Impact factor: 5.923

5.  Fructan synthesis, accumulation and polymer traits. II. Fructan pools in populations of perennial ryegrass (Lolium perenne L.) with variation for water-soluble carbohydrate and candidate genes were not correlated with biosynthetic activity and demonstrated constraints to polymer chain extension.

Authors:  Joe A Gallagher; Andrew J Cairns; David Thomas; Emma Timms-Taravella; Kirsten Skøt; Adam Charlton; Peter Williams; Lesley B Turner
Journal:  Front Plant Sci       Date:  2015-10-15       Impact factor: 5.753

6.  Effects of different carbohydrate sources on fructan metabolism in plants of Chrysolaena obovata grown in vitro.

Authors:  Flavio Trevisan; Vanessa F Oliveira; Maria A M Carvalho; Marília Gaspar
Journal:  Front Plant Sci       Date:  2015-09-07       Impact factor: 5.753

7.  Exogenous Classic Phytohormones Have Limited Regulatory Effects on Fructan and Primary Carbohydrate Metabolism in Perennial Ryegrass (Lolium perenne L.).

Authors:  Anna Gasperl; Annette Morvan-Bertrand; Marie-Pascale Prud'homme; Eric van der Graaff; Thomas Roitsch
Journal:  Front Plant Sci       Date:  2016-01-20       Impact factor: 5.753

Review 8.  Spatiotemporal Dynamics of Oligofructan Metabolism and Suggested Functions in Developing Cereal Grains.

Authors:  Manuela Peukert; Johannes Thiel; Hans-Peter Mock; Doris Marko; Winfriede Weschke; Andrea Matros
Journal:  Front Plant Sci       Date:  2016-01-19       Impact factor: 5.753

9.  Does gibberellin biosynthesis play a critical role in the growth of Lolium perenne? Evidence from a transcriptional analysis of gibberellin and carbohydrate metabolic genes after defoliation.

Authors:  Qianhe Liu; Chris S Jones; Anthony J Parsons; Hong Xue; Susanne Rasmussen
Journal:  Front Plant Sci       Date:  2015-11-03       Impact factor: 5.753

10.  A Simple and Fast Kinetic Assay for the Determination of Fructan Exohydrolase Activity in Perennial Ryegrass (Lolium perenne L.).

Authors:  Anna Gasperl; Annette Morvan-Bertrand; Marie-Pascale Prud'homme; Eric van der Graaff; Thomas Roitsch
Journal:  Front Plant Sci       Date:  2015-12-22       Impact factor: 5.753

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