Literature DB >> 25023361

Mitochondrial toxicity assessment in industry--a decade of technology development and insight.

Yvonne Will1, James Dykens.   

Abstract

Entities:  

Keywords:  drugs; liver injury; mitochondria; toxicity

Mesh：

Year:  2014        PMID： 25023361     DOI： 10.1517/17425255.2014.939628

Source DB:  PubMed          Journal:  Expert Opin Drug Metab Toxicol        ISSN： 1742-5255            Impact factor:   4.481


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  25 in total

1.  Development of a neurotoxicity assay that is tuned to detect mitochondrial toxicants.

Authors:  Johannes Delp; Melina Funke; Franziska Rudolf; Andrea Cediel; Susanne Hougaard Bennekou; Wanda van der Stel; Giada Carta; Paul Jennings; Cosimo Toma; Iain Gardner; Bob van de Water; Anna Forsby; Marcel Leist
Journal:  Arch Toxicol       Date:  2019-06-12       Impact factor: 5.153

Review 2.  Drug-induced liver injury: Advances in mechanistic understanding that will inform risk management.

Authors:  M Mosedale; P B Watkins
Journal:  Clin Pharmacol Ther       Date:  2017-01-11       Impact factor: 6.875

3.  Toluidine blue O directly and photodynamically impairs the bioenergetics of liver mitochondria: a potential mechanism of hepatotoxicity.

Authors:  Karina Borba Paulino Dos Santos; Ana Flavia Gatto Raimundo; Eduardo Makiyama Klosowski; Byanca Thais Lima de Souza; Márcio Shigueaki Mito; Renato Polimeni Constantin; Gislaine Cristiane Mantovanelli; Juliana Morais Mewes; Paulo Francisco Veiga Bizerra; Paulo Vinicius Moreira da Costa Menezes; Karina Sayuri Utsunomiya; Eduardo Hideo Gilglioni; Rogério Marchiosi; Wanderley Dantas Dos Santos; Osvaldo Ferrarese-Filho; Wilker Caetano; Paulo Cesar de Souza Pereira; Renato Sonchini Gonçalves; Jorgete Constantin; Emy Luiza Ishii-Iwamoto; Rodrigo Polimeni Constantin
Journal:  Photochem Photobiol Sci       Date:  2022-09-24       Impact factor: 4.328

4.  3D Spheroids of Human Primary Urine-Derived Stem Cells in the Assessment of Drug-Induced Mitochondrial Toxicity.

Authors:  Huifen Ding; Kalyani Jambunathan; Guochun Jiang; David M Margolis; Iris Leng; Michael Ihnat; Jian-Xing Ma; Jon Mirsalis; Yuanyuan Zhang
Journal:  Pharmaceutics       Date:  2022-05-11       Impact factor: 6.525

5.  Cell Morphological Profiling Enables High-Throughput Screening for PROteolysis TArgeting Chimera (PROTAC) Phenotypic Signature.

Authors:  Maria-Anna Trapotsi; Elizabeth Mouchet; Guy Williams; Tiziana Monteverde; Karolina Juhani; Riku Turkki; Filip Miljković; Anton Martinsson; Lewis Mervin; Kenneth R Pryde; Erik Müllers; Ian Barrett; Ola Engkvist; Andreas Bender; Kevin Moreau
Journal:  ACS Chem Biol       Date:  2022-07-06       Impact factor: 4.634

Review 6.  Prescription drugs and mitochondrial metabolism.

Authors:  Cameron A Schmidt
Journal:  Biosci Rep       Date:  2022-04-29       Impact factor: 3.976

Review 7.  Addressing the selectivity and toxicity of antiviral nucleosides.

Authors:  Joy Y Feng
Journal:  Antivir Chem Chemother       Date:  2018 Jan-Dec

8.  Physiologically Relevant Concentrations of Dolutegravir, Emtricitabine, and Efavirenz Induce Distinct Metabolic Alterations in HeLa Epithelial and BV2 Microglial Cells.

Authors:  Joseph W George; Jane E Mattingly; Nashanthea J Roland; Cassandra M Small; Benjamin G Lamberty; Howard S Fox; Kelly L Stauch
Journal:  Front Immunol       Date:  2021-05-20       Impact factor: 7.561

9.  In vitro prediction of organ toxicity: the challenges of scaling and secondary mechanisms of toxicity.

Authors:  Jan G Hengstler; Anna-Karin Sjögren; Daniele Zink; Jorrit J Hornberg
Journal:  Arch Toxicol       Date:  2020-02-17       Impact factor: 5.153

Review 10.  Why All the Fuss about Oxidative Phosphorylation (OXPHOS)?

Authors:  Yibin Xu; Ding Xue; Armand Bankhead; Nouri Neamati
Journal:  J Med Chem       Date:  2020-10-26       Impact factor: 8.039
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