Literature DB >> 25023070

Parasite load estimation by qPCR differentiates between asymptomatic and symptomatic infection in Indian visceral leishmaniasis.

Medhavi Sudarshan1, Shyam Sundar2.   

Abstract

Using quantitative PCR (qPCR), we differentiated asymptomatic and symptomatic Indian Leishmania donovani infection. qPCR on blood of 40 visceral leishmaniasis, 130 endemic, and 40 non-endemic healthy controls showed 500 times less (P < .0001) parasitemia in asymptomatic compared to the symptomatic ones and threshold of 5 parasite genome/mL for the clinical disease.
Copyright © 2014 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Asymptomatic; Visceral leishmaniasis; patients; qPCR

Mesh：

Substances：

Year:  2014        PMID： 25023070      PMCID： PMC4157122          DOI： 10.1016/j.diagmicrobio.2014.01.031

Source DB:  PubMed          Journal:  Diagn Microbiol Infect Dis        ISSN： 0732-8893            Impact factor:   2.803


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