Literature DB >> 25022899

Targeting Th17 cells in immune diseases.

Chen Dong1.   

Abstract

Last decade has seen quick developments in the understanding of a new type of T lymphocytes, Th17 cells. This information is benefiting the understanding and treatment of a variety of inflammatory diseases, as suggested by a recent paper in Immunity.

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Year:  2014        PMID: 25022899      PMCID: PMC4123301          DOI: 10.1038/cr.2014.92

Source DB:  PubMed          Journal:  Cell Res        ISSN: 1001-0602            Impact factor:   25.617


  12 in total

1.  Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis.

Authors:  Wolfgang Hueber; Dhavalkumar D Patel; Thaddeus Dryja; Andrew M Wright; Irina Koroleva; Gerard Bruin; Christian Antoni; Zoe Draelos; Michael H Gold; Patrick Durez; Paul P Tak; Juan J Gomez-Reino; C Stephen Foster; Rosa Y Kim; C Michael Samson; Naomi S Falk; David S Chu; David Callanan; Quan Dong Nguyen; Kristine Rose; Asifa Haider; Franco Di Padova
Journal:  Sci Transl Med       Date:  2010-10-06       Impact factor: 17.956

Review 2.  TH17 cells in development: an updated view of their molecular identity and genetic programming.

Authors:  Chen Dong
Journal:  Nat Rev Immunol       Date:  2008-05       Impact factor: 53.106

3.  Cigarette smoke induction of osteopontin (SPP1) mediates T(H)17 inflammation in human and experimental emphysema.

Authors:  Ming Shan; Xiaoyi Yuan; Li-Zhen Song; Luz Roberts; Nazanin Zarinkamar; Alexander Seryshev; Yiqun Zhang; Susan Hilsenbeck; Seon-Hee Chang; Chen Dong; David B Corry; Farrah Kheradmand
Journal:  Sci Transl Med       Date:  2012-01-18       Impact factor: 17.956

Review 4.  The many faces of Th17 cells.

Authors:  Anneli Peters; Youjin Lee; Vijay K Kuchroo
Journal:  Curr Opin Immunol       Date:  2011-09-06       Impact factor: 7.486

5.  Cutting edge: in vitro generated Th17 cells maintain their cytokine expression program in normal but not lymphopenic hosts.

Authors:  Roza Nurieva; Xuexian O Yang; Yeonseok Chung; Chen Dong
Journal:  J Immunol       Date:  2009-03-01       Impact factor: 5.422

6.  Small-molecule RORγt antagonists inhibit T helper 17 cell transcriptional network by divergent mechanisms.

Authors:  Sheng Xiao; Nir Yosef; Jianfei Yang; Yonghui Wang; Ling Zhou; Chen Zhu; Chuan Wu; Erkan Baloglu; Darby Schmidt; Radha Ramesh; Mercedes Lobera; Mark S Sundrud; Pei-Yun Tsai; Zhijun Xiang; Jinsong Wang; Yan Xu; Xichen Lin; Karsten Kretschmer; Peter B Rahl; Richard A Young; Zhong Zhong; David A Hafler; Aviv Regev; Shomir Ghosh; Alexander Marson; Vijay K Kuchroo
Journal:  Immunity       Date:  2014-04-17       Impact factor: 31.745

7.  Impaired T(H)17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome.

Authors:  Joshua D Milner; Jason M Brenchley; Arian Laurence; Alexandra F Freeman; Brenna J Hill; Kevin M Elias; Yuka Kanno; Christine Spalding; Houda Z Elloumi; Michelle L Paulson; Joie Davis; Amy Hsu; Ava I Asher; John O'Shea; Steven M Holland; William E Paul; Daniel C Douek
Journal:  Nature       Date:  2008-03-12       Impact factor: 49.962

8.  A validated regulatory network for Th17 cell specification.

Authors:  Maria Ciofani; Aviv Madar; Carolina Galan; Maclean Sellars; Kieran Mace; Florencia Pauli; Ashish Agarwal; Wendy Huang; Christopher N Parkhurst; Michael Muratet; Kim M Newberry; Sarah Meadows; Alex Greenfield; Yi Yang; Preti Jain; Francis K Kirigin; Carmen Birchmeier; Erwin F Wagner; Kenneth M Murphy; Richard M Myers; Richard Bonneau; Dan R Littman
Journal:  Cell       Date:  2012-09-25       Impact factor: 41.582

9.  Plasticity of Th17 cells in Peyer's patches is responsible for the induction of T cell-dependent IgA responses.

Authors:  Keiji Hirota; Jan-Eric Turner; Matteo Villa; João H Duarte; Jocelyne Demengeot; Oliver M Steinmetz; Brigitta Stockinger
Journal:  Nat Immunol       Date:  2013-03-10       Impact factor: 25.606

10.  Regulation of inflammatory responses by IL-17F.

Authors:  Xuexian O Yang; Seon Hee Chang; Heon Park; Roza Nurieva; Bhavin Shah; Luis Acero; Yi-Hong Wang; Kimberly S Schluns; Russell R Broaddus; Zhou Zhu; Chen Dong
Journal:  J Exp Med       Date:  2008-04-14       Impact factor: 14.307

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  12 in total

1.  Proteasome inhibition suppresses Th17 cell generation and ameliorates autoimmune development in experimental Sjögren's syndrome.

Authors:  Fan Xiao; Xiang Lin; Jie Tian; Xiaohui Wang; Qian Chen; Ke Rui; Jie Ma; Shengjun Wang; Qingwen Wang; Xiaoqi Wang; Dongzhou Liu; Lingyun Sun; Liwei Lu
Journal:  Cell Mol Immunol       Date:  2017-07-10       Impact factor: 11.530

2.  Discovery of Biaryl Amides as Potent, Orally Bioavailable, and CNS Penetrant RORγt Inhibitors.

Authors:  Yonghui Wang; Wei Cai; Yaobang Cheng; Ting Yang; Qian Liu; Guifeng Zhang; Qinghua Meng; Fangbin Han; Yafei Huang; Ling Zhou; Zhijun Xiang; Yong-Gang Zhao; Yan Xu; Ziqiang Cheng; Sijie Lu; Qianqian Wu; Jia-Ning Xiang; John D Elliott; Stewart Leung; Feng Ren; Xichen Lin
Journal:  ACS Med Chem Lett       Date:  2015-05-26       Impact factor: 4.345

3.  IL-21R signaling is critical for induction of spontaneous experimental autoimmune encephalomyelitis.

Authors:  Youjin Lee; Meike Mitsdoerffer; Sheng Xiao; Guangxiang Gu; Raymond A Sobel; Vijay K Kuchroo
Journal:  J Clin Invest       Date:  2015-09-28       Impact factor: 14.808

4.  From RORγt Agonist to Two Types of RORγt Inverse Agonists.

Authors:  Yonghui Wang; Wei Cai; Ting Tang; Qian Liu; Ting Yang; Liuqing Yang; Yingli Ma; Guifeng Zhang; Yafei Huang; Xiaoxia Song; Lisa A Orband-Miller; Qianqian Wu; Ling Zhou; Zhijun Xiang; Jia-Ning Xiang; Stewart Leung; Liming Shao; Xichen Lin; Mercedes Lobera; Feng Ren
Journal:  ACS Med Chem Lett       Date:  2018-01-22       Impact factor: 4.345

5.  Th17 cell-derived IL-17A promoted tumor progression via STAT3/NF-κB/Notch1 signaling in non-small cell lung cancer.

Authors:  Ruirui Wang; Li Yang; Chaoqi Zhang; Ruijie Wang; Zhen Zhang; Qianyi He; Xinfeng Chen; Bin Zhang; Zhihai Qin; Liping Wang; Yi Zhang
Journal:  Oncoimmunology       Date:  2018-08-23       Impact factor: 8.110

6.  Adiponectin Suppresses T Helper 17 Cell Differentiation and Limits Autoimmune CNS Inflammation via the SIRT1/PPARγ/RORγt Pathway.

Authors:  Kai Zhang; Yawei Guo; Zhenzhen Ge; Zhihui Zhang; Yurong Da; Wen Li; Zimu Zhang; Zhenyi Xue; Yan Li; Yinghui Ren; Long Jia; Koon-Ho Chan; Fengrui Yang; Jun Yan; Zhi Yao; Aimin Xu; Rongxin Zhang
Journal:  Mol Neurobiol       Date:  2016-08-11       Impact factor: 5.590

Review 7.  Th17 response in patients with cervical cancer.

Authors:  Jayra Juliana Paiva Alves; Thales Allyrio Araújo De Medeiros Fernandes; Josélio Maria Galvão De Araújo; Ricardo Ney Oliveira Cobucci; Daniel Carlos Ferreira Lanza; Fabiana Lima Bezerra; Vânia Sousa Andrade; José Veríssimo Fernandes
Journal:  Oncol Lett       Date:  2018-09-21       Impact factor: 2.967

8.  Target identification among known drugs by deep learning from heterogeneous networks.

Authors:  Xiangxiang Zeng; Siyi Zhu; Weiqiang Lu; Zehui Liu; Jin Huang; Yadi Zhou; Jiansong Fang; Yin Huang; Huimin Guo; Lang Li; Bruce D Trapp; Ruth Nussinov; Charis Eng; Joseph Loscalzo; Feixiong Cheng
Journal:  Chem Sci       Date:  2020-01-13       Impact factor: 9.969

9.  Arid5a regulates naive CD4+ T cell fate through selective stabilization of Stat3 mRNA.

Authors:  Kazuya Masuda; Barry Ripley; Kishan Kumar Nyati; Praveen Kumar Dubey; Mohammad Mahabub-Uz Zaman; Hamza Hanieh; Mitsuru Higa; Kazuo Yamashita; Daron M Standley; Tsukasa Mashima; Masato Katahira; Toru Okamoto; Yoshiharu Matsuura; Osamu Takeuchi; Tadamitsu Kishimoto
Journal:  J Exp Med       Date:  2016-03-28       Impact factor: 14.307

10.  Ordering Knowledge in the Markers of Psychiatric/Mental Disorders.

Authors:  Napoleon Waszkiewicz
Journal:  J Clin Med       Date:  2022-01-06       Impact factor: 4.241

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