Literature DB >> 25019069

NCOA5, a molecular link between type 2 diabetes and liver cancer.

Connie Y Liu1, Gen-Sheng Feng1.   

Abstract

It is reported that nuclear receptor co-activator 5 (NCOA5) is a possible susceptibility gene to both type 2 diabetes (T2D) and hepatocellular carcinoma (HCC). The link between these two diseases is an important area of study with the growing prevalence of T2D. Thus, discovery of a genetic link may have great impact on the field. The group used NCOA5 (+/-) mice to observe the effects of the gene's haploinsufficiency on the symptoms of T2D and HCC and claimed NCOA5's regulation of IL-6 in the pathogenesis of the diseases.

Entities:  

Keywords:  Nuclear receptor co-activator 5 (NCOA5); hepatocarcinoma; type 2 dibetes (T2D)

Year:  2014        PMID： 25019069      PMCID： PMC4073315          DOI： 10.3978/j.issn.2304-3881.2014.04.02

Source DB:  PubMed          Journal:  Hepatobiliary Surg Nutr        ISSN： 2304-3881            Impact factor:   7.293


  9 in total

Review 1.  NF-κB and STAT3 - key players in liver inflammation and cancer.

Authors:  Guobin He; Michael Karin
Journal:  Cell Res       Date:  2010-12-28       Impact factor: 25.617

2.  Identification of liver cancer progenitors whose malignant progression depends on autocrine IL-6 signaling.

Authors:  Guobin He; Debanjan Dhar; Hayato Nakagawa; Joan Font-Burgada; Hisanobu Ogata; Yuhong Jiang; Shabnam Shalapour; Ekihiro Seki; Shawn E Yost; Kristen Jepsen; Kelly A Frazer; Olivier Harismendy; Maria Hatziapostolou; Dimitrios Iliopoulos; Atsushi Suetsugu; Robert M Hoffman; Ryosuke Tateishi; Kazuhiko Koike; Michael Karin
Journal:  Cell       Date:  2013-10-10       Impact factor: 41.582

3.  NCOA5 haploinsufficiency results in glucose intolerance and subsequent hepatocellular carcinoma.

Authors:  Shenglan Gao; Aimin Li; Feiye Liu; Fengsheng Chen; Mark Williams; Chengliang Zhang; Zakiya Kelley; Chin-Lee Wu; Rongcheng Luo; Hua Xiao
Journal:  Cancer Cell       Date:  2013-12-09       Impact factor: 31.743

Review 4.  The global epidemiology of hepatocellular carcinoma: present and future.

Authors:  Katherine A McGlynn; W Thomas London
Journal:  Clin Liver Dis       Date:  2011-05       Impact factor: 6.126

Review 5.  Hepatocellular carcinoma: epidemiology, surveillance, and diagnosis.

Authors:  Morris Sherman
Journal:  Semin Liver Dis       Date:  2010-02-19       Impact factor: 6.115

Review 6.  Hepatocellular carcinoma.

Authors:  Alejandro Forner; Josep M Llovet; Jordi Bruix
Journal:  Lancet       Date:  2012-02-20       Impact factor: 79.321

7.  Heterogeneity in gene loci associated with type 2 diabetes on human chromosome 20q13.1.

Authors:  J L Bento; N D Palmer; M Zhong; B Roh; J P Lewis; M R Wing; H Pandya; B I Freedman; C D Langefeld; S S Rich; D W Bowden; J C Mychaleckyj
Journal:  Genomics       Date:  2008-08-09       Impact factor: 5.736

8.  Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production.

Authors:  Willscott E Naugler; Toshiharu Sakurai; Sunhwa Kim; Shin Maeda; Kyounghyun Kim; Ahmed M Elsharkawy; Michael Karin
Journal:  Science       Date:  2007-07-06       Impact factor: 47.728

Review 9.  The influence of diabetes in the pathogenesis and the clinical course of hepatocellular carcinoma: recent findings and new perspectives.

Authors:  Antonio Facciorusso
Journal:  Curr Diabetes Rev       Date:  2013-09
  9 in total
  7 in total

1.  Association between expression of nuclear receptor co-activator 5 protein and prognosis in postoperative patients with osteosarcoma.

Authors:  Ya Wu; Jian Wu; Qi-Rong Dong; Nai-Zhou Guo
Journal:  Oncol Lett       Date:  2017-12-05       Impact factor: 2.967

2.  Clinical and metabolomics analysis of hepatocellular carcinoma patients with diabetes mellitus.

Authors:  Hongping Xia; Jianxiang Chen; Karthik Sekar; Ming Shi; Tian Xie; Kam M Hui
Journal:  Metabolomics       Date:  2019-11-26       Impact factor: 4.290

Review 3.  A Nonlinear Model for Gene-Based Gene-Environment Interaction.

Authors:  Jian Sa; Xu Liu; Tao He; Guifen Liu; Yuehua Cui
Journal:  Int J Mol Sci       Date:  2016-06-04       Impact factor: 5.923

4.  Clinical significance of NCOA5 gene rs2903908 polymorphism in Behçet's disease.

Authors:  Aydin Rustemoglu; Esra Erkol Inal; Ahmet Inanir; Duygu Ekinci; Ulker Gul; Serbulent Yigit; Omer Ates; Nevin Karakus
Journal:  EXCLI J       Date:  2017-05-04       Impact factor: 4.068

5.  Altered DNA methylation in children born to mothers with rheumatoid arthritis during pregnancy.

Authors:  Hilal Ince-Askan; Pooja R Mandaviya; Janine F Felix; Liesbeth Duijts; Joyce B van Meurs; Johanna M W Hazes; Radboud J E M Dolhain
Journal:  Ann Rheum Dis       Date:  2019-05-29       Impact factor: 19.103

Review 6.  Mechanisms Underlying Hepatocellular Carcinoma Progression in Patients with Type 2 Diabetes.

Authors:  Tingting Shi; Hideki Kobara; Kyoko Oura; Tsutomu Masaki
Journal:  J Hepatocell Carcinoma       Date:  2021-02-11

Review 7.  Iron at the Interface of Hepatocellular Carcinoma.

Authors:  Rossana Paganoni; André Lechel; Maja Vujic Spasic
Journal:  Int J Mol Sci       Date:  2021-04-15       Impact factor: 5.923
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.