Literature DB >> 25017611

Endometrial pathology in postmenopausal women with no bleeding.

M Genc1, B Genc, N Sahin, E Celik, G A Turan, E B Gur, S Guclu.   

Abstract

OBJECTIVE: The aim of this study was to determine the rate of unexpected uterine pathology in postmenopausal women admitted to a gynecology clinic with symptoms other than vaginal bleeding and who were scheduled to undergo hysterectomy.
MATERIALS AND METHODS: We reviewed retrospectively the medical records of 283 postmenopausal patients who had gynecological surgery between September 2007 and January 2014. We reviewed their presenting symptoms on admission, the indications for surgery, and their transvaginal ultrasonographic findings. Postoperative histopathological results based on uterine specimens were also recorded. The results were analyzed statistically.
RESULTS: Of 283 patients who had surgery, 209 had no vaginal bleeding at the time of admission. From this group, 75.6% were found to have unsuspected pathology, including endometrial hyperplasia, endometrial polyps, uterine fibroids, adenomyosis, and one case of endometrial carcinoma (0.5%). The remaining 74 patients had experienced postmenopausal bleeding and in 87.8% there were pathological findings including 13 cases (17.6%) of endometrial cancer (p = 0.0001).
CONCLUSION: Vaginal bleeding in postmenopausal women is indicative of a wide array of gynecological pathologies, including endometrial carcinoma. However, uterine fibroids, pelvic masses, or even endometrial cancer may develop without co-morbid vaginal bleeding. Therefore we advocate that postmenopausal women should undergo yearly screening and consultation, without waiting for an episode of vaginal bleeding.

Entities:  

Keywords:  ENDOMETRIUM; NO VAGINAL BLEEDING; POSTMENOPAUSAL; SCREENING

Mesh:

Year:  2014        PMID: 25017611     DOI: 10.3109/13697137.2014.944152

Source DB:  PubMed          Journal:  Climacteric        ISSN: 1369-7137            Impact factor:   3.005


  2 in total

1.  Hysteroscopy: A necessary method for detecting uterine pathologies in post-menopausal women with abnormal uterine bleeding or increased endometrial thickness.

Authors:  Fatemeh Sarvi; Ashraf Alleyassin; Marzieh Aghahosseini; Marzieh Ghasemi; Sima Gity
Journal:  Turk J Obstet Gynecol       Date:  2016-12-15

2.  Jie-Yu Pill, A Proprietary Herbal Medicine, Ameliorates Mood Disorder-Like Behavior and Cognitive Impairment in Estrogen-Deprived Mice Exposed to Chronic Unpredictable Mild Stress: Implication for a Potential Therapy of Menopause Syndrome.

Authors:  Xi-Dan Zhou; Xin-Jing Yang; Yu Zheng; Zong-Shi Qin; Wei Sha; Gang Chen; Zhang-Jin Zhang
Journal:  Front Psychiatry       Date:  2020-10-29       Impact factor: 4.157

  2 in total

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