Literature DB >> 25014712

Recent approaches to chemical discovery and development against malaria and the neglected tropical diseases human African trypanosomiasis and schistosomiasis.

Mathew Njoroge, Nicholas M Njuguna, Peggoty Mutai, Dennis S B Ongarora, Paul W Smith1, Kelly Chibale.   

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Year:  2014        PMID： 25014712     DOI： 10.1021/cr500098f

Source DB:  PubMed          Journal:  Chem Rev        ISSN： 0009-2665            Impact factor:   60.622


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  26 in total

1.  Insights into structural and physicochemical properties required for β-hematin inhibition of privileged triarylimidazoles.

Authors:  Clinton G L Veale; Janeeka Jayram; Shivani Naidoo; Dustin Laming; Tarryn Swart; Tania Olivier; Matthew P Akerman; Katherine A de Villiers; Heinrich C Hoppe; Vineet Jeena
Journal:  RSC Med Chem       Date:  2019-12-16

Review 2.  Repurposing strategies for tropical disease drug discovery.

Authors:  Dana M Klug; Michael H Gelb; Michael P Pollastri
Journal:  Bioorg Med Chem Lett       Date:  2016-03-30       Impact factor: 2.823

Review 3.  Chemotherapy for human schistosomiasis: how far have we come? What's new? Where do we go from here?

Authors:  Godwin Akpeko Dziwornu; Henrietta Dede Attram; Samuel Gachuhi; Kelly Chibale
Journal:  RSC Med Chem       Date:  2020-04-06

Review 4.  Novel lead compounds in pre-clinical development against African sleeping sickness.

Authors:  Michael Berninger; Ines Schmidt; Alicia Ponte-Sucre; Ulrike Holzgrabe
Journal:  Medchemcomm       Date:  2017-07-31       Impact factor: 3.597

Review 5.  Modern approaches to accelerate discovery of new antischistosomal drugs.

Authors:  Bruno Junior Neves; Eugene Muratov; Renato Beilner Machado; Carolina Horta Andrade; Pedro Vitor Lemos Cravo
Journal:  Expert Opin Drug Discov       Date:  2016-05-03       Impact factor: 6.098

Review 6.  Biological Activity of Recently Discovered Halogenated Marine Natural Products.

Authors:  Gordon W Gribble
Journal:  Mar Drugs       Date:  2015-06-30       Impact factor: 5.118

7.  Multicomponent reaction-based synthesis and biological evaluation of tricyclic heterofused quinolines with multi-trypanosomatid activity.

Authors:  Ornella Di Pietro; Esther Vicente-García; Martin C Taylor; Diana Berenguer; Elisabet Viayna; Anna Lanzoni; Irene Sola; Helena Sayago; Cristina Riera; Roser Fisa; M Victòria Clos; Belén Pérez; John M Kelly; Rodolfo Lavilla; Diego Muñoz-Torrero
Journal:  Eur J Med Chem       Date:  2015-10-19       Impact factor: 6.514

Review 8.  The Role of Nitroreductases in Resistance to Nitroimidazoles.

Authors:  Carol Thomas; Christopher D Gwenin
Journal:  Biology (Basel)       Date:  2021-05-01

9.  Reactions of N,3-diarylpropiolamides with arenes under superelectrophilic activation: synthesis of 4,4-diaryl-3,4-dihydroquinolin-2(1H)-ones and their derivatives.

Authors:  Larisa Yu Gurskaya; Diana S Belyanskaya; Dmitry S Ryabukhin; Denis I Nilov; Irina A Boyarskaya; Aleksander V Vasilyev
Journal:  Beilstein J Org Chem       Date:  2016-05-11       Impact factor: 2.883

10.  Synthesis and biological evaluation of N-cyanoalkyl-, N-aminoalkyl-, and N-guanidinoalkyl-substituted 4-aminoquinoline derivatives as potent, selective, brain permeable antitrypanosomal agents.

Authors:  Irene Sola; Albert Artigas; Martin C Taylor; F Javier Pérez-Areales; Elisabet Viayna; M Victòria Clos; Belén Pérez; Colin W Wright; John M Kelly; Diego Muñoz-Torrero
Journal:  Bioorg Med Chem       Date:  2016-08-22       Impact factor: 3.641
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