Literature DB >> 25013160

Does TP53 guard ALL genomes?

Anthony V Moorman1.   

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Year:  2014        PMID： 25013160      PMCID： PMC4093675          DOI： 10.1182/blood-2014-05-576934

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


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  8 in total

1.  Acute lymphoblastic leukemia with low hypodiploid/near triploid karyotype is a specific clinical entity and exhibits a very high TP53 mutation frequency of 93%.

Authors:  Verena Mühlbacher; Melanie Zenger; Susanne Schnittger; Sandra Weissmann; Franziska Kunze; Alexander Kohlmann; Frauke Bellos; Wolfgang Kern; Torsten Haferlach; Claudia Haferlach
Journal:  Genes Chromosomes Cancer       Date:  2014-03-11       Impact factor: 5.006

2.  Mutations and deletions of the TP53 gene predict nonresponse to treatment and poor outcome in first relapse of childhood acute lymphoblastic leukemia.

Authors:  Jana Hof; Stefanie Krentz; Claudia van Schewick; Gabriele Körner; Shabnam Shalapour; Peter Rhein; Leonid Karawajew; Wolf-Dieter Ludwig; Karl Seeger; Günter Henze; Arend von Stackelberg; Christian Hagemeier; Cornelia Eckert; Renate Kirschner-Schwabe
Journal:  J Clin Oncol       Date:  2011-07-11       Impact factor: 44.544

3.  Key pathways are frequently mutated in high-risk childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group.

Authors:  Jinghui Zhang; Charles G Mullighan; Richard C Harvey; Gang Wu; Xiang Chen; Michael Edmonson; Kenneth H Buetow; William L Carroll; I-Ming Chen; Meenakshi Devidas; Daniela S Gerhard; Mignon L Loh; Gregory H Reaman; Mary V Relling; Bruce M Camitta; W Paul Bowman; Malcolm A Smith; Cheryl L Willman; James R Downing; Stephen P Hunger
Journal:  Blood       Date:  2011-06-16       Impact factor: 22.113

4.  p53-Dependent transcriptional repression of c-myc is required for G1 cell cycle arrest.

Authors:  Jenny S L Ho; Weili Ma; Daniel Y L Mao; Samuel Benchimol
Journal:  Mol Cell Biol       Date:  2005-09       Impact factor: 4.272

5.  The genomic landscape of hypodiploid acute lymphoblastic leukemia.

Authors:  Linda Holmfeldt; Lei Wei; Ernesto Diaz-Flores; Michael Walsh; Jinghui Zhang; Li Ding; Debbie Payne-Turner; Michelle Churchman; Anna Andersson; Shann-Ching Chen; Kelly McCastlain; Jared Becksfort; Jing Ma; Gang Wu; Samir N Patel; Susan L Heatley; Letha A Phillips; Guangchun Song; John Easton; Matthew Parker; Xiang Chen; Michael Rusch; Kristy Boggs; Bhavin Vadodaria; Erin Hedlund; Christina Drenberg; Sharyn Baker; Deqing Pei; Cheng Cheng; Robert Huether; Charles Lu; Robert S Fulton; Lucinda L Fulton; Yashodhan Tabib; David J Dooling; Kerri Ochoa; Mark Minden; Ian D Lewis; L Bik To; Paula Marlton; Andrew W Roberts; Gordana Raca; Wendy Stock; Geoffrey Neale; Hans G Drexler; Ross A Dickins; David W Ellison; Sheila A Shurtleff; Ching-Hon Pui; Raul C Ribeiro; Meenakshi Devidas; Andrew J Carroll; Nyla A Heerema; Brent Wood; Michael J Borowitz; Julie M Gastier-Foster; Susana C Raimondi; Elaine R Mardis; Richard K Wilson; James R Downing; Stephen P Hunger; Mignon L Loh; Charles G Mullighan
Journal:  Nat Genet       Date:  2013-01-20       Impact factor: 38.330

Review 6.  The significance of TP53 in lymphoid malignancies: mutation prevalence, regulation, prognostic impact and potential as a therapeutic target.

Authors:  K-John J Cheung; Douglas E Horsman; Randy D Gascoyne
Journal:  Br J Haematol       Date:  2009-06-03       Impact factor: 6.998

7.  TP53 mutations occur in 15.7% of ALL and are associated with MYC-rearrangement, low hypodiploidy, and a poor prognosis.

Authors:  Anna Stengel; Susanne Schnittger; Sandra Weissmann; Sabrina Kuznia; Wolfgang Kern; Alexander Kohlmann; Torsten Haferlach; Claudia Haferlach
Journal:  Blood       Date:  2014-05-14       Impact factor: 22.113

8.  Karyotype is an independent prognostic factor in adult acute lymphoblastic leukemia (ALL): analysis of cytogenetic data from patients treated on the Medical Research Council (MRC) UKALLXII/Eastern Cooperative Oncology Group (ECOG) 2993 trial.

Authors:  Anthony V Moorman; Christine J Harrison; Georgina A N Buck; Sue M Richards; Lorna M Secker-Walker; Mary Martineau; Gail H Vance; Athena M Cherry; Rodney R Higgins; Adele K Fielding; Letizia Foroni; Elisabeth Paietta; Martin S Tallman; Mark R Litzow; Peter H Wiernik; Jacob M Rowe; Anthony H Goldstone; Gordon W Dewald
Journal:  Blood       Date:  2006-12-14       Impact factor: 22.113
  8 in total
  1 in total

Review 1.  Near-Haploidy and Low-Hypodiploidy in B-Cell Acute Lymphoblastic Leukemia: When Less Is Too Much.

Authors:  Oscar Molina; Alex Bataller; Namitha Thampi; Jordi Ribera; Isabel Granada; Pablo Velasco; José Luis Fuster; Pablo Menéndez
Journal:  Cancers (Basel)       Date:  2021-12-22       Impact factor: 6.639
  1 in total

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