W Trzepizur1, F Gagnadoux2. 1. Département de pneumologie, CHU d'Angers, 4, rue Larrey, 49033 Angers cedex 9, France; Inserm, U1063, université d'Angers, Angers, France. Electronic address: wotrzepizur@chu-angers.fr. 2. Département de pneumologie, CHU d'Angers, 4, rue Larrey, 49033 Angers cedex 9, France; Inserm, U1063, université d'Angers, Angers, France.
Abstract
INTRODUCTION: Epidemiological cohorts based on population samples, established in the 1990s, have helped to clarify the prevalence of obstructive sleep apnoea syndrome (OSAS) and to identify key risk factors and co-morbidities. STATE OF KNOWLEDGE: OSAS is a common disease whose prevalence increases with age. Its main risk factor is obesity, but familial and genetic predisposition may also promote the condition. The association of OSAS with increased cardiovascular mortality has been known for several years and has been confirmed by recent data from epidemiological cohorts showing increased mortality including an increased incidence of coronary events and stroke in particular in men aged below 70 years. Recent studies also show an independent association between OSAS and cancer mortality. CONCLUSIONS: OSAS is a common disease whose prevalence continues to increase with the increase of obesity in the population. Large epidemiological studies have shown an independent relationship between OSAS and cardiovascular diseases, metabolic disorders and more recently cancer.
INTRODUCTION: Epidemiological cohorts based on population samples, established in the 1990s, have helped to clarify the prevalence of obstructive sleep apnoea syndrome (OSAS) and to identify key risk factors and co-morbidities. STATE OF KNOWLEDGE: OSAS is a common disease whose prevalence increases with age. Its main risk factor is obesity, but familial and genetic predisposition may also promote the condition. The association of OSAS with increased cardiovascular mortality has been known for several years and has been confirmed by recent data from epidemiological cohorts showing increased mortality including an increased incidence of coronary events and stroke in particular in men aged below 70 years. Recent studies also show an independent association between OSAS and cancer mortality. CONCLUSIONS: OSAS is a common disease whose prevalence continues to increase with the increase of obesity in the population. Large epidemiological studies have shown an independent relationship between OSAS and cardiovascular diseases, metabolic disorders and more recently cancer.
Authors: Giannicola Iannella; Giuseppe Magliulo; Cristina Anna Maria Lo Iacono; Irene Claudia Visconti; Jerome R Lechien; Tiziano Perrone; Giovanni Cammaroto; Giuseppe Meccariello; Antonino Maniaci; Salvatore Cocuzza; Milena Di Luca; Andrea De Vito; Chiara Martone; Antonella Polimeni; Antonio Greco; Marco de Vincentiis; Massimo Ralli; Annalisa Pace; Giampiero Gulotta; Stefano Pelucchi; Angelo Eplite; Claudio Vicini Journal: J Clin Med Date: 2022-04-23 Impact factor: 4.964
Authors: Letizia Lonia; Marco Scalese; Gianluca Rossato; Giovanni Bruno; Francesca Zalunardo; Alberto De Stefani; Antonio Gracco Journal: Medicina (Kaunas) Date: 2020-06-30 Impact factor: 2.430