OBJECTIVE: To check whether subtle voiding dysfunction is related to recurrent urinary tract infection (rUTI). METHODS: 254 consecutive patients with at least four episodes of urinary tract infection (UTI) were studied. At least three repeat urodynamic evaluations with an additional ice water test to maximize the detection of involuntary detrusor contraction (IDC) were used. Stress urinary incontinence cases were used as controls. Nonparametric univariate and multivariate analyses were used for statistics. RESULTS: IDC was detected in 83.6% of patients in the rUTI group and in 31.7% in the control group. IDC was <15 cm H2O in 54.7% whereas high-amplitude (>50 cm H2O) IDC was observed in 6.8% in the rUTI group. Female urinary tract obstruction was diagnosed in 16.8% of patients in the rUTI group and in 7.9% in the control group. Residual volume, PdetQmax and Qmax were not predictive of UTI recurrence. Symptoms were similar in both groups. CONCLUSIONS: Patients with rUTI present with covert bladder dysfunctions represented by detrusor overactivity.
OBJECTIVE: To check whether subtle voiding dysfunction is related to recurrent urinary tract infection (rUTI). METHODS: 254 consecutive patients with at least four episodes of urinary tract infection (UTI) were studied. At least three repeat urodynamic evaluations with an additional ice water test to maximize the detection of involuntary detrusor contraction (IDC) were used. Stress urinary incontinence cases were used as controls. Nonparametric univariate and multivariate analyses were used for statistics. RESULTS: IDC was detected in 83.6% of patients in the rUTI group and in 31.7% in the control group. IDC was <15 cm H2O in 54.7% whereas high-amplitude (>50 cm H2O) IDC was observed in 6.8% in the rUTI group. Female urinary tract obstruction was diagnosed in 16.8% of patients in the rUTI group and in 7.9% in the control group. Residual volume, PdetQmax and Qmax were not predictive of UTI recurrence. Symptoms were similar in both groups. CONCLUSIONS:Patients with rUTI present with covert bladder dysfunctions represented by detrusor overactivity.
Authors: William Stuart Reynolds; Elizabeth Timbrook Brown; Jill Danford; Melissa Kaufman; Alan Wein; Roger Dmochowski; Stephen Bruehl Journal: Neurourol Urodyn Date: 2016-07-19 Impact factor: 2.696
Authors: Jeremy N Reese; Marc J Rogers; Zhiying Xiao; Bing Shen; Jicheng Wang; Zeyad Schwen; James R Roppolo; William C de Groat; Changfeng Tai Journal: Am J Physiol Renal Physiol Date: 2015-02-11