Literature DB >> 25010939

Stereoselective synthesis of cis-2-fluorocyclopropanecarboxylic acid.

Taku Shibue1, Yasumichi Fukuda.   

Abstract

A rhodium-catalyzed cyclopropanation of 1-fluoro-1-(phenylsulfonyl)ethylene and diazo esters is described as an effective method for the stereoselective synthesis of cis-2-fluorocyclopropanecarboxylic acid. This process provides an example of the cyclopropanation of electron-deficient olefin and diazoacetates.

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Year:  2014        PMID： 25010939     DOI： 10.1021/jo501219n

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  3 in total

1.  Synthesis and Deployment of an Elusive Fluorovinyl Cation Equivalent: Access to Quaternary α-(1'-Fluoro)vinyl Amino Acids as Potential PLP Enzyme Inactivators.

Authors:  Christopher D McCune; Matthew L Beio; Jill M Sturdivant; Roberto de la Salud-Bea; Brendan M Darnell; David B Berkowitz
Journal:  J Am Chem Soc       Date:  2017-09-28       Impact factor: 15.419

2.  Divergent Synthesis of Cyclopropane-Containing Lead-Like Compounds, Fragments and Building Blocks through a Cobalt Catalyzed Cyclopropanation of Phenyl Vinyl Sulfide.

Authors:  Stephen J Chawner; Manuel J Cases-Thomas; James A Bull
Journal:  European J Org Chem       Date:  2017-09-11

3.  Oxidative β-C-H sulfonylation of cyclic amines.

Authors:  R J Griffiths; W C Kong; S A Richards; G A Burley; M C Willis; E P A Talbot
Journal:  Chem Sci       Date:  2018-01-22       Impact factor: 9.825
  3 in total

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