Dina Baddar1,2, Debra A Goldstein1. 1. a Department of Ophthalmology , Northwestern University, Feinberg School of Medicine , Chicago , Illinois , USA and. 2. b Al Watany Eye Hospital , Cairo , Egypt.
Abstract
PURPOSE: To report the first documented case of HLA-A29(+) birdshot chorioretinopathy in a Hispanic patient. CASE DESCRIPTION: A 62-year-old female from Mexico presented with a 15-year history of progressive nyctalopia, floaters, and decreasing vision. She carried multiple previous diagnoses, including posterior vitreous detachment and macular edema. Both fundi showed characteristic creamy ill-defined lesions of birdshot chorioretinopathy, mostly atrophic, with evidence of old periphlebitis and arteriolar attenuation. Bilateral macular atrophy resulted in compromised visual acuity. Workup revealed positive HLA-A29 and was negative for TB and syphilis. CONCLUSION: Despite having been reported almost exclusively in non-Hispanic Caucasians, HLA-A29-positive birdshot chorioretinopathy may occur in Hispanic patients. This patient's ethnicity may have resulted in a significant delay in diagnosis.
PURPOSE: To report the first documented case of HLA-A29(+) birdshot chorioretinopathy in a Hispanic patient. CASE DESCRIPTION: A 62-year-old female from Mexico presented with a 15-year history of progressive nyctalopia, floaters, and decreasing vision. She carried multiple previous diagnoses, including posterior vitreous detachment and macular edema. Both fundi showed characteristic creamy ill-defined lesions of birdshot chorioretinopathy, mostly atrophic, with evidence of old periphlebitis and arteriolar attenuation. Bilateral macular atrophy resulted in compromised visual acuity. Workup revealed positive HLA-A29 and was negative for TB and syphilis. CONCLUSION: Despite having been reported almost exclusively in non-Hispanic Caucasians, HLA-A29-positive birdshot chorioretinopathy may occur in Hispanic patients. This patient's ethnicity may have resulted in a significant delay in diagnosis.
Authors: Maria Luisa Gois da Fonsêca; Raul N G Vianna; Anna C H Rocha; Antonio M B Casella; Arnaldo Cialdini; Cristina Muccioli; Daniela S da Costa; Daniel R Lucena; Daniel V Vasconcelos-Santos; Eduardo Morizot; Elaine Castro; Ever E C Rodriguez; Felipe T Diligenti; Fernanda B O Porto; Heloisa Nascimento; Joyce H Yanamoto; Juliana L Oréfice; Lilia R P Muralha; Luciana B Carneiro; Luciana P S Finamor; Maria A M Frazão; Mario Motta; Mario J Nobrega; Moyses E Zajdenweber; Remo T Moraes; Rodrigo L Meirelles; Sidney R Lemos; Wilton Feitosa de Araújo Journal: Int J Retina Vitreous Date: 2022-01-07