Literature DB >> 25009446

Proton beam therapy for localized prostate cancer 101: basics, controversies, and facts.

Eric S Wisenbaugh1, Paul E Andrews1, Robert G Ferrigni1, Steven E Schild2, Sameer R Keole2, William W Wong2, Sujay A Vora2.   

Abstract

Proton beam therapy for prostate cancer has become a source of controversy in the urologic community, and the rapid dissemination and marketing of this technology has led to many patients inquiring about this therapy. Yet the complexity of the technology, the cost, and the conflicting messages in the literature have left many urologists ill equipped to counsel their patients regarding this option. This article reviews the basic science of the proton beam, examines the reasons for both the hype and the controversy surrounding this therapy, and, most importantly, examines the literature so that every urologist is able to comfortably discuss this option with inquiring patients.

Entities:  

Keywords:  External beam radiation therapy; Intensity modulated radiation therapy; Prostate cancer; Proton beam therapy

Year:  2014        PMID: 25009446      PMCID: PMC4080851     

Source DB:  PubMed          Journal:  Rev Urol        ISSN: 1523-6161


  28 in total

1.  Potential role of intensity modulated proton beams in prostate cancer radiotherapy.

Authors:  L Cella; A Lomax; R Miralbell
Journal:  Int J Radiat Oncol Biol Phys       Date:  2001-01-01       Impact factor: 7.038

2.  Early outcomes from three prospective trials of image-guided proton therapy for prostate cancer.

Authors:  Nancy P Mendenhall; Zuofeng Li; Bradford S Hoppe; Robert B Marcus; William M Mendenhall; R Charles Nichols; Christopher G Morris; Christopher R Williams; Joseph Costa; Randal Henderson
Journal:  Int J Radiat Oncol Biol Phys       Date:  2010-11-17       Impact factor: 7.038

3.  Dose-volume comparison of proton therapy and intensity-modulated radiotherapy for prostate cancer.

Authors:  Carlos Vargas; Amber Fryer; Chaitali Mahajan; Daniel Indelicato; David Horne; Angela Chellini; Craig McKenzie; Paula Lawlor; Randal Henderson; Zuofeng Li; Liyong Lin; Kenneth Olivier; Sameer Keole
Journal:  Int J Radiat Oncol Biol Phys       Date:  2007-09-27       Impact factor: 7.038

Review 4.  Proton-beam therapy for prostate cancer.

Authors:  A Robert Kagan; Robert J Schulz
Journal:  Cancer J       Date:  2010 Sep-Oct       Impact factor: 3.360

5.  Comparative treatment planning on localized prostate carcinoma conformal photon- versus proton-based radiotherapy.

Authors:  Ulrike Mock; Joachim Bogner; Dietmar Georg; Thomas Auberger; Richard Pötter
Journal:  Strahlenther Onkol       Date:  2005-07       Impact factor: 3.621

6.  Dose-response in radiotherapy for localized prostate cancer: results of the Dutch multicenter randomized phase III trial comparing 68 Gy of radiotherapy with 78 Gy.

Authors:  Stephanie T H Peeters; Wilma D Heemsbergen; Peter C M Koper; Wim L J van Putten; Annerie Slot; Michel F H Dielwart; Johannes M G Bonfrer; Luca Incrocci; Joos V Lebesque
Journal:  J Clin Oncol       Date:  2006-05-01       Impact factor: 44.544

7.  70 Gy versus 80 Gy in localized prostate cancer: 5-year results of GETUG 06 randomized trial.

Authors:  Véronique Beckendorf; Stéphane Guerif; Elisabeth Le Prisé; Jean-Marc Cosset; Agnes Bougnoux; Bruno Chauvet; Naji Salem; Olivier Chapet; Sylvain Bourdain; Jean-Marc Bachaud; Philippe Maingon; Jean-Michel Hannoun-Levi; Luc Malissard; Jean-Marc Simon; Pascal Pommier; Men Hay; Bernard Dubray; Jean-Léon Lagrange; Elisabeth Luporsi; Pierre Bey
Journal:  Int J Radiat Oncol Biol Phys       Date:  2010-12-14       Impact factor: 7.038

8.  Randomized trial comparing conventional-dose with high-dose conformal radiation therapy in early-stage adenocarcinoma of the prostate: long-term results from proton radiation oncology group/american college of radiology 95-09.

Authors:  Anthony L Zietman; Kyounghwa Bae; Jerry D Slater; William U Shipley; Jason A Efstathiou; John J Coen; David A Bush; Margie Lunt; Daphna Y Spiegel; Rafi Skowronski; B Rodney Jabola; Carl J Rossi
Journal:  J Clin Oncol       Date:  2010-02-01       Impact factor: 44.544

9.  Is proton beam therapy cost effective in the treatment of adenocarcinoma of the prostate?

Authors:  Andre Konski; William Speier; Alexandra Hanlon; J Robert Beck; Alan Pollack
Journal:  J Clin Oncol       Date:  2007-08-20       Impact factor: 44.544

10.  Radiation dose escalation for localized prostate cancer: intensity-modulated radiotherapy versus permanent transperineal brachytherapy.

Authors:  William W Wong; Sujay A Vora; Steven E Schild; Gary A Ezzell; Paul E Andrews; Robert G Ferrigni; Scott K Swanson
Journal:  Cancer       Date:  2009-12-01       Impact factor: 6.860

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  8 in total

1.  Arrests reveal debate about costs and benefits of proton therapy.

Authors:  Amanda B Keener
Journal:  Nat Med       Date:  2014-10       Impact factor: 53.440

Review 2.  Proton therapy for prostate cancer: current state and future perspectives.

Authors:  Yao-Yu Wu; Kang-Hsing Fan
Journal:  Br J Radiol       Date:  2021-09-24       Impact factor: 3.039

Review 3.  Quality of care and economic considerations of active surveillance of men with prostate cancer.

Authors:  Christopher P Filson
Journal:  Transl Androl Urol       Date:  2018-04

4.  Tobacco Smoking, Lung Cancer, and Therapy in Iraq: Current Perspective.

Authors:  Buthainah A Ibrahim; Saif Al-Humaish; Mohammed A I Al-Obaide
Journal:  Front Public Health       Date:  2018-10-26

5.  Assessment of Polyethylene Glycol Hydrogel Spacer and Its Effect on Rectal Radiation Dose in Prostate Cancer Patients Receiving Proton Beam Radiation Therapy.

Authors:  Anojan Navaratnam; Jameson Cumsky; Haidar Abdul-Muhsin; Justin Gagneur; Jiajian Shen; Heidi Kosiorek; Michael Golafshar; Akira Kawashima; William Wong; Robert Ferrigni; Mitchell R Humphreys
Journal:  Adv Radiat Oncol       Date:  2019-09-05

6.  A study of the clinical, treatment planning and dosimetric feasibility of dose painting in external beam radiotherapy of prostate cancer.

Authors:  Steve W Blake; Alison Stapleton; Andrew Brown; Sian Curtis; Janice Ash-Miles; Emma Dennis; Susan Masson; Dawn Bowers; Serena Hilman
Journal:  Phys Imaging Radiat Oncol       Date:  2020-08-10

7.  Comparison of Estimated Late Toxicities between IMPT and IMRT Based on Multivariable NTCP Models for High-Risk Prostate Cancers Treated with Pelvic Nodal Radiation.

Authors:  Srinivas Chilukuri; Sham Sundar; Kartikeswar Patro; Mayur Sawant; Rangasamy Sivaraman; Manikandan Arjunan; Pankaj Kumar Panda; Dayananda Sharma; Rakesh Jalali
Journal:  Int J Part Ther       Date:  2022-06-13

Review 8.  Harnessing the potential of multimodal radiotherapy in prostate cancer.

Authors:  Yiannis Philippou; Hanna Sjoberg; Alastair D Lamb; Philip Camilleri; Richard J Bryant
Journal:  Nat Rev Urol       Date:  2020-05-01       Impact factor: 14.432

  8 in total

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