Literature DB >> 25008902

Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in Colombian patients with AIDS for diagnosis and follow-up during therapy.

Diego H Caceres1, Christina M Scheel2, Angela M Tobón3, Angela Ahlquist Cleveland2, Angela Restrepo1, Mary E Brandt2, Tom Chiller2, Beatriz L Gómez4.   

Abstract

We validated an antigen capture enzyme-linked immunosorbent assay (ELISA) in Colombian persons with AIDS and proven histoplasmosis and evaluated the correlation between antigenuria and clinical improvement during follow-up. The sensitivity of the Histoplasma capsulatum ELISA was 86%, and the overall specificity was 94%. The antigen test successfully monitored the response to therapy.
Copyright © 2014, American Society for Microbiology. All Rights Reserved.

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Year:  2014        PMID： 25008902      PMCID： PMC4178582          DOI： 10.1128/CVI.00101-14

Source DB:  PubMed          Journal:  Clin Vaccine Immunol        ISSN： 1556-679X


  14 in total

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Journal:  Transpl Infect Dis       Date:  2006-12       Impact factor: 2.228

Review 2.  American histoplasmosis in developing countries with a special focus on patients with HIV: diagnosis, treatment, and prognosis.

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Journal:  Curr Opin Infect Dis       Date:  2006-10       Impact factor: 4.915

3.  Detection of histoplasma antigen by a quantitative enzyme immunoassay.

Authors:  Patricia A Connolly; Michelle M Durkin; Ann M Lemonte; Emily J Hackett; L Joseph Wheat
Journal:  Clin Vaccine Immunol       Date:  2007-10-03

4.  Clinical prediction model for differentiation of disseminated Histoplasma capsulatum and Mycobacterium avium complex infections in febrile patients with AIDS.

Authors:  E A Graviss; E A Vanden Heuvel; C E Lacke; S A Spindel; A C White; R J Hamill
Journal:  J Acquir Immune Defic Syndr       Date:  2000-05-01       Impact factor: 3.731

5.  Cross-reactivity in Histoplasma capsulatum variety capsulatum antigen assays of urine samples from patients with endemic mycoses.

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Review 7.  Diagnosis of histoplasmosis in immunosuppressed patients.

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Journal:  Curr Opin Infect Dis       Date:  2008-08       Impact factor: 4.915

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Authors:  Ben De Pauw; Thomas J Walsh; J Peter Donnelly; David A Stevens; John E Edwards; Thierry Calandra; Peter G Pappas; Johan Maertens; Olivier Lortholary; Carol A Kauffman; David W Denning; Thomas F Patterson; Georg Maschmeyer; Jacques Bille; William E Dismukes; Raoul Herbrecht; William W Hope; Christopher C Kibbler; Bart Jan Kullberg; Kieren A Marr; Patricia Muñoz; Frank C Odds; John R Perfect; Angela Restrepo; Markus Ruhnke; Brahm H Segal; Jack D Sobel; Tania C Sorrell; Claudio Viscoli; John R Wingard; Theoklis Zaoutis; John E Bennett
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9.  Production and evaluation of reagents for detection of Histoplasma capsulatum antigenuria by enzyme immunoassay.

Authors:  Mark D Lindsley; Heather L Holland; Sandra L Bragg; Steven F Hurst; Kathleen A Wannemuehler; Christine J Morrison
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10.  Disseminated histoplasmosis in HIV-infected patients in South America: a neglected killer continues on its rampage.

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Journal:  PLoS Negl Trop Dis       Date:  2013-11-21
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  15 in total

Review 1.  Antigen Detection in the Diagnosis of Histoplasmosis: A Meta-analysis of Diagnostic Performance.

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2.  High Mortality and Coinfection in a Prospective Cohort of Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome Patients with Histoplasmosis in Guatemala.

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Journal:  Am J Trop Med Hyg       Date:  2017-07       Impact factor: 2.345

3.  Implementation of a Training Course Increased the Diagnosis of Histoplasmosis in Colombia.

Authors:  Diego H Caceres; Alejandra Zuluaga; Karen Arango-Bustamante; Catalina de Bedout; Ángela Maria Tobón; Ángela Restrepo; Beatriz L Gómez; Luz Elena Cano; Ángel González
Journal:  Am J Trop Med Hyg       Date:  2015-06-29       Impact factor: 2.345

4.  Multicenter Validation of Commercial Antigenuria Reagents To Diagnose Progressive Disseminated Histoplasmosis in People Living with HIV/AIDS in Two Latin American Countries.

Authors:  Diego H Cáceres; Blanca E Samayoa; Eduardo E Arathoon; Beatriz L Gómez; Narda G Medina; Angela M Tobón; Brenda J Guzmán; Danicela Mercado; Angela Restrepo; Tom Chiller
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Review 5.  Diagnosis of histoplasmosis: current status and perspectives.

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6.  Histoplasma capsulatum 100-kilodalton antigen: recombinant production, characterization, and evaluation of its possible application in the diagnosis of histoplasmosis.

Authors:  María A Toscanini; Daniel González Maglio; Paula Capece; Gladys Posse; Cristina A Iovannitti; Alejandro D Nusblat; María L Cuestas
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Review 7.  Minimizing fungal disease deaths will allow the UNAIDS target of reducing annual AIDS deaths below 500 000 by 2020 to be realized.

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8.  AIDS-Defining Illnesses at Initial Diagnosis of HIV in a Large Guatemalan Cohort.

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9.  Standardization and validation of real time PCR assays for the diagnosis of histoplasmosis using three molecular targets in an animal model.

Authors:  Luisa F López; César O Muñoz; Diego H Cáceres; Ángela M Tobón; Vladimir Loparev; Oliver Clay; Tom Chiller; Anastasia Litvintseva; Lalitha Gade; Ángel González; Beatriz L Gómez
Journal:  PLoS One       Date:  2017-12-29       Impact factor: 3.240

10.  Discovery of a unique Mycobacterium tuberculosis protein through proteomic analysis of urine from patients with active tuberculosis.

Authors:  Nira Pollock; Rakesh Dhiman; Nada Daifalla; Maha Farhat; Antonio Campos-Neto
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