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Literature DB >> 25008332

A case of toxic epidermal necrolysis caused by trimethoprim-sulfamethoxazole.

Jharendra P Rijal¹, Tiffany Pompa², Smith Giri³, Vijaya Raj Bhatt⁴.

Abstract

Toxic epidermal necrolysis (TEN) is a rare but serious dermatological emergency characterised by diffuse exfoliation of the skin and mucous membranes due to immune mediated destruction of the epidermis which can lead to sepsis and respiratory distress. Trimethoprim-sulfamethoxazole is a widely used antibiotic which can rarely lead to TEN. Early diagnosis and aggressive medical care is essential for the reduction of high morbidity and mortality associated with this disease. We present a case of successfully recovered TEN due to trimethoprim-sulfamethoxazole in a 62-year-old woman. 2014 BMJ Publishing Group Ltd.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 2014 PMID： 25008332 PMCID： PMC4091412 DOI： 10.1136/bcr-2013-203163

Source DB: PubMed Journal: BMJ Case Rep ISSN： 1757-790X

21 in total

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Authors: I Garcia-Doval; L LeCleach; H Bocquet; X L Otero; J C Roujeau
Journal: Arch Dermatol Date: 2000-03

A case of toxic epidermal necrolysis caused by trimethoprim-sulfamethoxazole.

Review 1. Toxic epidermal necrolysis.

Review 2. Joining the DoTS: new approach to classifying adverse drug reactions.

Review 3. Toxic epidermal necrolysis: review of pathogenesis and management.

4. Granulysin as a marker for early diagnosis of the Stevens-Johnson syndrome.

Review 5. Drug-induced toxic epidermal necrolysis.

6. Toxic epidermal necrolysis and Stevens-Johnson syndrome: does early withdrawal of causative drugs decrease the risk of death?

7. Trimethoprim-sulfamethoxazole-induced Stevens-Johnson syndrome: a case report.

Review 8. Toxic epidermal necrolysis (Lyell's disease).

9. The culprit drugs in 87 cases of toxic epidermal necrolysis (Lyell's syndrome).

10. Clinical classification of cases of toxic epidermal necrolysis, Stevens-Johnson syndrome, and erythema multiforme.

1. Early Manifestations of Toxic Epidermal Necrolysis.