Gaëlle Chevallereau1, Xavier Gleyses1, Laurène Roussel1, Sarah Hamdan1, Olivier Beauchet2, Cédric Annweiler3. 1. Medical School, University of Angers, UNAM, Angers, France; 2. Department of Neuroscience, Division of Geriatric Medicine, Angers University Hospital; Angers University Memory Clinic; UPRES EA 4638, University of Angers, UNAM, Angers, France; 3. Department of Neuroscience, Division of Geriatric Medicine, Angers University Hospital; Angers University Memory Clinic; UPRES EA 4638, University of Angers, UNAM, Angers, France;, and Robarts Research Institute, Department of Medical Biophysics, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, Ontario, Canada.
Abstract
BACKGROUND: Diet is a major exogenous source of vitamin D. The objective of this analysis was to determine whether the yes/no answer to a simple question exploring diet ("Do you eat fatty fish at least once a week and/or eggs several times per week?") could be associated with serum 25-hydroxy-vitamin D status among 261 older in- and outpatients (mean ± standard deviation, 83.5 ± 8.1 years). METHODS: Two groups were distinguished based on the binary yes/no answer. Hypovitaminosis D was defined as serum 25-hydroxyvitamin D ≤ 75 nmol/L. RESULTS: More participants with hypovitaminosis D answered "No" to the question on diet compared to their counterparts (p = 0.002). Answering "No" was associated with hypovitaminosis D (OR = 3.22, p = 0.001) after adjustment for potential confounders, with a positive predictive value = 79 %. CONCLUSION: A simple dietary question may identify older patients with hypovitaminosis D who should receive vitamin D supplements.
BACKGROUND: Diet is a major exogenous source of vitamin D. The objective of this analysis was to determine whether the yes/no answer to a simple question exploring diet ("Do you eat fatty fish at least once a week and/or eggs several times per week?") could be associated with serum 25-hydroxy-vitamin D status among 261 older in- and outpatients (mean ± standard deviation, 83.5 ± 8.1 years). METHODS: Two groups were distinguished based on the binary yes/no answer. Hypovitaminosis D was defined as serum 25-hydroxyvitamin D ≤ 75 nmol/L. RESULTS: More participants with hypovitaminosis D answered "No" to the question on diet compared to their counterparts (p = 0.002). Answering "No" was associated with hypovitaminosis D (OR = 3.22, p = 0.001) after adjustment for potential confounders, with a positive predictive value = 79 %. CONCLUSION: A simple dietary question may identify older patients with hypovitaminosis D who should receive vitamin D supplements.
Authors: Barbara Altieri; Etienne Cavalier; Harjit Pal Bhattoa; Faustino R Pérez-López; María T López-Baena; Gonzalo R Pérez-Roncero; Peter Chedraui; Cedric Annweiler; Silvia Della Casa; Sieglinde Zelzer; Markus Herrmann; Antongiulio Faggiano; Annamaria Colao; Michael F Holick Journal: Eur J Clin Nutr Date: 2020-01-06 Impact factor: 4.016