Rahul Manchanda1, Ross Norman2, Ashok Malla3, Rajendra Harricharan4, Sandra Northcott5, Julie Richard6. 1. Director-Prevention and Early Intervention Program for Psychoses (PEPP), London Health Sciences Centre-Victoria Hospital, London, Ontario; Professor of Psychiatry, The University of Western Ontario, London, Ontario. 2. Professor, Departments of Psychiatry, and Epidemiology and Biostatistics, The University of Western Ontario, London, Ontario; Research Psychologist- PEPP, London Health Sciences Centre, London, Ontario. 3. Director-PEPP Montréal, Douglas Institute, Montréal, Quebec; Professor and Canada Research Chair in Early Psychosis, Department of Psychiatry, McGill University, Montreal, Quebec. 4. Associate Professor, Department of Psychiatry, The University of Western Ontario, London, Ontario; Consultant-PEPP, London Health Sciences Centre, London, Ontario. 5. Associate Professor, Department of Psychiatry, The University of Western Ontario, London, Ontario; Consultant-PEPP, Department of Psychiatry, London Health Sciences Centre, London, Ontario. 6. Assistant Professor, Department of Psychiatry, The University of Western Ontario, London, Ontario; Consultant-PEPP, Department of Psychiatry, London Health Sciences Centre, London, Ontario.
Abstract
OBJECTIVE: To examine the relation of electroencephalographic abnormalities to 5-year outcomes in first-episode psychosis (FEP). METHODS: Patients (n = 103) had their baseline electroencephalogram (EEG) classified by modified Mayo Clinic criteria. Symptoms and psychosocial functioning were rated after 5 years of treatment. RESULTS: Dysrhythmic EEG was associated with persistence in positive and negative symptoms of psychoses and poorer psychosocial functioning at 5-year follow-up, independently of other characteristics, such as duration of untreated illness or premorbid adjustment. A higher percentage of people with comorbid substance use disorder had normal EEG. CONCLUSIONS: Abnormal baseline EEG in FEP is associated with poorer 5-year symptomatic and functional outcome.
OBJECTIVE: To examine the relation of electroencephalographic abnormalities to 5-year outcomes in first-episode psychosis (FEP). METHODS:Patients (n = 103) had their baseline electroencephalogram (EEG) classified by modified Mayo Clinic criteria. Symptoms and psychosocial functioning were rated after 5 years of treatment. RESULTS: Dysrhythmic EEG was associated with persistence in positive and negative symptoms of psychoses and poorer psychosocial functioning at 5-year follow-up, independently of other characteristics, such as duration of untreated illness or premorbid adjustment. A higher percentage of people with comorbid substance use disorder had normal EEG. CONCLUSIONS: Abnormal baseline EEG in FEP is associated with poorer 5-year symptomatic and functional outcome.
Authors: Niall Crumlish; Peter Whitty; Mary Clarke; Stephen Browne; Moayyad Kamali; Maurice Gervin; Orfhlaith McTigue; Anthony Kinsella; John L Waddington; Conall Larkin; Eadbhard O'Callaghan Journal: Br J Psychiatry Date: 2009-01 Impact factor: 9.319
Authors: Murat Yücel; Emre Bora; Dan I Lubman; Nadia Solowij; Warrick J Brewer; Sue M Cotton; Philippe Conus; Michael J Takagi; Alex Fornito; Stephen J Wood; Patrick D McGorry; Christos Pantelis Journal: Schizophr Bull Date: 2010-07-25 Impact factor: 9.306
Authors: Jaana Suvisaari; Outi Mantere; Jaakko Keinänen; Teemu Mäntylä; Eva Rikandi; Maija Lindgren; Tuula Kieseppä; Tuukka T Raij Journal: Front Psychiatry Date: 2018-11-13 Impact factor: 4.157