Literature DB >> 25007222

The HIV-1 Env trimer in HD.

James B Munro1, Walther Mothes2.   

Abstract

Understanding the structure of the native HIV-1 envelope spike protein is critical for the development of vaccines and antiviral therapies. In this issue of Structure, Guttman and colleagues use hydrogen-deuterium exchange (HDX) to provide new insights into the structure of the HIV-1 Env trimer and enhance our understanding of how HIV-1 Env is activated for virus fusion.
Copyright © 2014 Elsevier Ltd. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2014        PMID： 25007222      PMCID： PMC4094347          DOI： 10.1016/j.str.2014.06.004

Source DB:  PubMed          Journal:  Structure        ISSN： 0969-2126            Impact factor:   5.006


  9 in total

1.  Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer.

Authors:  Dmitry Lyumkis; Jean-Philippe Julien; Natalia de Val; Albert Cupo; Clinton S Potter; Per-Johan Klasse; Dennis R Burton; Rogier W Sanders; John P Moore; Bridget Carragher; Ian A Wilson; Andrew B Ward
Journal:  Science       Date:  2013-10-31       Impact factor: 47.728

2.  Crystal structure of a soluble cleaved HIV-1 envelope trimer.

Authors:  Jean-Philippe Julien; Albert Cupo; Devin Sok; Robyn L Stanfield; Dmitry Lyumkis; Marc C Deller; Per-Johan Klasse; Dennis R Burton; Rogier W Sanders; John P Moore; Andrew B Ward; Ian A Wilson
Journal:  Science       Date:  2013-10-31       Impact factor: 47.728

3.  A recombinant human immunodeficiency virus type 1 envelope glycoprotein complex stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits is an antigenic mimic of the trimeric virion-associated structure.

Authors:  J M Binley; R W Sanders; B Clas; N Schuelke; A Master; Y Guo; F Kajumo; D J Anselma; P J Maddon; W C Olson; J P Moore
Journal:  J Virol       Date:  2000-01       Impact factor: 5.103

4.  Molecular architecture of native HIV-1 gp120 trimers.

Authors:  Jun Liu; Alberto Bartesaghi; Mario J Borgnia; Guillermo Sapiro; Sriram Subramaniam
Journal:  Nature       Date:  2008-07-30       Impact factor: 49.962

5.  Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility.

Authors:  Marie Pancera; Shahzad Majeed; Yih-En Andrew Ban; Lei Chen; Chih-chin Huang; Leopold Kong; Young Do Kwon; Jonathan Stuckey; Tongqing Zhou; James E Robinson; William R Schief; Joseph Sodroski; Richard Wyatt; Peter D Kwong
Journal:  Proc Natl Acad Sci U S A       Date:  2009-12-28       Impact factor: 11.205

6.  A functional interaction between gp41 and gp120 is observed for monomeric but not oligomeric, uncleaved HIV-1 Env gp140.

Authors:  Miklos Guttman; Kelly K Lee
Journal:  J Virol       Date:  2013-08-21       Impact factor: 5.103

7.  Cleavage strongly influences whether soluble HIV-1 envelope glycoprotein trimers adopt a native-like conformation.

Authors:  Rajesh P Ringe; Rogier W Sanders; Anila Yasmeen; Helen J Kim; Jeong Hyun Lee; Albert Cupo; Jacob Korzun; Ronald Derking; Thijs van Montfort; Jean-Philippe Julien; Ian A Wilson; Per Johan Klasse; Andrew B Ward; John P Moore
Journal:  Proc Natl Acad Sci U S A       Date:  2013-10-21       Impact factor: 11.205

8.  CD4-induced activation in a soluble HIV-1 Env trimer.

Authors:  Miklos Guttman; Natalie K Garcia; Albert Cupo; Tsutomu Matsui; Jean-Philippe Julien; Rogier W Sanders; Ian A Wilson; John P Moore; Kelly K Lee
Journal:  Structure       Date:  2014-06-12       Impact factor: 5.006

9.  A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies.

Authors:  Rogier W Sanders; Ronald Derking; Albert Cupo; Jean-Philippe Julien; Anila Yasmeen; Natalia de Val; Helen J Kim; Claudia Blattner; Alba Torrents de la Peña; Jacob Korzun; Michael Golabek; Kevin de Los Reyes; Thomas J Ketas; Marit J van Gils; C Richter King; Ian A Wilson; Andrew B Ward; P J Klasse; John P Moore
Journal:  PLoS Pathog       Date:  2013-09-19       Impact factor: 6.823
  9 in total
  3 in total

Review 1.  Shake, rattle, and roll: Impact of the dynamics of flavivirus particles on their interactions with the host.

Authors:  Richard J Kuhn; Kimberly A Dowd; Carol Beth Post; Theodore C Pierson
Journal:  Virology       Date:  2015-03-30       Impact factor: 3.616

2.  Illuminating the virus life cycle with single-molecule FRET imaging.

Authors:  Maolin Lu; Xiaochu Ma; Walther Mothes
Journal:  Adv Virus Res       Date:  2019-08-20       Impact factor: 9.937

3.  Evolution of Multiple Domains of the HIV-1 Envelope Glycoprotein during Coreceptor Switch with CCR5 Antagonist Therapy.

Authors:  Yueqi Du; Ellen Wu; Xiang Gao; Jie Zhang; John C Martin; Bruce A Rosa; Makedonka Mitreva; Lee Ratner
Journal:  Microbiol Spectr       Date:  2022-06-21
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.