Literature DB >> 25006429

Cardiopulmonary exercise testing suggests a beneficial response to pulmonary endarterectomy in a patient with chronic thromboembolic obstruction and normal preoperative pulmonary hemodynamics.

Colm McCabe1, Stephen D Preston1, Deepa Gopalan1, John Dunning1, Joanna Pepke-Zaba1.   

Abstract

Pulmonary endarterectomy offers a symptomatic and survival benefit in patients with chronic thromboembolic pulmonary hypertension through sustained improvement in right ventricular function. However, its role in patients with symptom limitation, chronic thrombotic obstruction, and a normal pulmonary hemodynamic profile is less clear. Cardiopulmonary exercise testing (CPET) stresses the cardiopulmonary system and has a characteristic response in pulmonary hypertension. CPET may therefore reveal abnormalities in patients with chronic thrombotic obstruction where hemodynamic investigations conducted at rest are reassuring. Using incremental CPET, we demonstrated improvements in right ventricular performance and ventilatory efficiency following pulmonary endarterecomy in a patient with preoperative exercise limitation and normal pulmonary hemodynamics. Careful evaluation of exercise responses may extend the potential benefit offered by pulmonary endarterectomy in patients with chronic thromboembolic obstruction irrespective of their resting hemodynamic profile.

Entities:  

Year:  2014        PMID: 25006429      PMCID: PMC4070752          DOI: 10.1086/674878

Source DB:  PubMed          Journal:  Pulm Circ        ISSN: 2045-8932            Impact factor:   3.017


  3 in total

Review 1.  Chronic thromboembolic pulmonary hypertension.

Authors:  Marius M Hoeper; Eckhard Mayer; Gérald Simonneau; Lewis J Rubin
Journal:  Circulation       Date:  2006-04-25       Impact factor: 29.690

2.  Pulmonary endarterectomy improves dyspnea by the relief of dead space ventilation.

Authors:  Mart N van der Plas; Herre J Reesink; Carel M Roos; Reindert P van Steenwijk; Jaap J Kloek; Paul Bresser
Journal:  Ann Thorac Surg       Date:  2010-02       Impact factor: 4.330

3.  Pulmonary endarterectomy: outcomes in patients aged >70.

Authors:  Marius Berman; Gillian Hardman; Linda Sharples; Joanna Pepke-Zaba; Karen Sheares; Steven Tsui; John Dunning; David P Jenkins
Journal:  Eur J Cardiothorac Surg       Date:  2012-06       Impact factor: 4.191

  3 in total
  2 in total

1.  Case report: Subjective loss of performance after pulmonary embolism in an athlete- beyond normal values.

Authors:  Daniel Dumitrescu; Felix Gerhardt; Thomas Viethen; Matthias Schmidt; Eckhard Mayer; Stephan Rosenkranz
Journal:  BMC Pulm Med       Date:  2016-01-28       Impact factor: 3.317

2.  Pulmonary endarterectomy for patients with chronic thromboembolic disease.

Authors:  Şehnaz Olgun Yıldızeli; Alper Kepez; Serpil Taş; Mehmed Yanartaş; Ali Fuad Durusoy; Atakan Erkılınç; Bülent Mutlu; Cihangir Kaymaz; Hasan Sunar; Bedrettin Yıldızeli
Journal:  Anatol J Cardiol       Date:  2018-04       Impact factor: 1.596

  2 in total

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