| Literature DB >> 2500391 |
S Rogne1, O Myklebost, B Høyheim, B Olaisen, T Gedde-Dahl.
Abstract
We have cloned a cDNA probe for human apolipoprotein AII and used it to analyze linkage relationships on chromosome 1. We found no recombinations between APOA2 and the gene coding for the Duffy blood group antigens (FY) in the 19 meioses examined. Our maximal lod score is 4.2 at zero recombination rate. K. Berg (1987, Cytogenet. Cell Genet. 46:579) found a maximal score of 2.5 at recombination fraction 0.14 in 54 meioses. When results from both studies are combined, the most likely distance between FY and APOA2 is about 10% recombination with a combined lod score of 5.6 for both sexes.Entities:
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Year: 1989 PMID: 2500391 DOI: 10.1016/0888-7543(89)90296-6
Source DB: PubMed Journal: Genomics ISSN: 0888-7543 Impact factor: 5.736