Literature DB >> 25003844

Total glossectomy without laryngectomy - a review of functional outcomes and reconstructive principles.

Matthew H Rigby1, Richard E Hayden.   

Abstract

PURPOSE OF REVIEW: To provide an overview of functional outcomes and reconstructive principles of total glossectomy without laryngectomy reported in recent series, and the evidence regarding which patients are at risk for poor functional outcomes. RECENT
FINDINGS: After total glossectomy with laryngeal preservation gastric tube dependency ranges from 30 to 44% for primary treatment. Between 85 and 95% of patients are able to have their tracheostomy tube removed. Many patients can also regain meaningfully intelligible speech. In the setting of prior radiation or chemoradiation therapy, achieving oral diet and tracheostomy decannulation is less likely.Reconstructions must have sufficient bulk to allow for contact with the palate, and achievement of this vertical height has been shown to be associated with improved speech and swallowing outcomes. Laryngeal suspension is an important adjunct to prevent both laryngeal prolapse and minimize aspiration risk. The role of either sensory or motor reinnervation is unclear, although there is currently more evidence for the benefit of sensory reinnervation.
SUMMARY: With meticulous reconstructive technique and appropriate patient selection, total glossectomy with laryngeal preservation can be performed as a primary or salvage procedure with acceptable functional outcomes.

Entities:  

Mesh:

Year:  2014        PMID: 25003844     DOI: 10.1097/MOO.0000000000000076

Source DB:  PubMed          Journal:  Curr Opin Otolaryngol Head Neck Surg        ISSN: 1068-9508            Impact factor:   2.064


  5 in total

1.  Prediction of decannulation, oral intake recovery, overall survival and lung metastasis following oral malignant tumor resection and reconstruction.

Authors:  Hidenori Suzuki; Ikuo Hyodo; Yasuhisa Hasegawa
Journal:  Oncol Lett       Date:  2017-12-11       Impact factor: 2.967

2.  Total or subtotal glossectomy with laryngeal preservation: a national study of 29 patients.

Authors:  Harri Keski-Säntti; Leif Bäck; Patrik Lassus; Petri Koivunen; Ilpo Kinnunen; Henry Blomster; Antti A Mäkitie; Katri Aro
Journal:  Eur Arch Otorhinolaryngol       Date:  2017-11-08       Impact factor: 2.503

3.  Pectoralis Major Myocutaneous Flap for Head and Neck Defects in the Era of Free Flaps: Harvesting Technique and Indications.

Authors:  Muyuan Liu; Weiwei Liu; Xihong Yang; Haipeng Guo; Hanwei Peng
Journal:  Sci Rep       Date:  2017-04-07       Impact factor: 4.379

4.  Comparison of Treatment Outcomes Between Total and Near Total Glossectomy with Larynx Preservation and Flap Reconstruction: A Single Institution Experience with 23 Patients.

Authors:  Uygar Levent Demir; Mustafa Aslıer; Hakkı Caner İnan
Journal:  Turk Arch Otorhinolaryngol       Date:  2022-08-31

5.  Combination of NTP with cetuximab inhibited invasion/migration of cetuximab-resistant OSCC cells: Involvement of NF-κB signaling.

Authors:  Jae Won Chang; Sung Un Kang; Yoo Seob Shin; Seong Jin Seo; Yeon Soo Kim; Sang Sik Yang; Jong-Soo Lee; Eunpyo Moon; Keunho Lee; Chul-Ho Kim
Journal:  Sci Rep       Date:  2015-12-14       Impact factor: 4.379

  5 in total

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