AIM: THE AIM OF THE PRESENT STUDY WAS TO EVALUATE THE BIOCOMPATIBILITY OF A NEW PULP CAPPING MATERIAL (BIODENTINE, SEPTODONT) COMPARED WITH REFERENCE PULP CAPPING MATERIALS: Dycal (Dentsply), ProRoot MTA (Dentsply) and MTA-Angelus (Angelus) by using murine odontoblast cell line and Alamar blue and MTT cytotoxicity tests. METHODS: The citocompatibility of murine odontoblasts cells (MDPC-23) were evaluated at different times using a 24 Transwell culture plate by Alamar blue test and MTT assay. RESULTS: The results were significantly different among the pulp capping materials tested. Biocompatibility was significant different among materials with different composition. CONCLUSIONS: Biodentine and MTA-based products show lower cytotoxicity varying from calcium hydroxide-based material which present higher citotoxicity.
AIM: THE AIM OF THE PRESENT STUDY WAS TO EVALUATE THE BIOCOMPATIBILITY OF A NEW PULP CAPPING MATERIAL (BIODENTINE, SEPTODONT) COMPARED WITH REFERENCE PULP CAPPING MATERIALS: Dycal (Dentsply), ProRoot MTA (Dentsply) and MTA-Angelus (Angelus) by using murine odontoblast cell line and Alamar blue and MTTcytotoxicity tests. METHODS: The citocompatibility of murine odontoblasts cells (MDPC-23) were evaluated at different times using a 24 Transwell culture plate by Alamar blue test and MTT assay. RESULTS: The results were significantly different among the pulp capping materials tested. Biocompatibility was significant different among materials with different composition. CONCLUSIONS:Biodentine and MTA-based products show lower cytotoxicity varying from calcium hydroxide-based material which present higher citotoxicity.
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