Literature DB >> 25002884

Strontium ranelate improves delayed healing of osteolytic lesions of the jaw in a man with chronic osteomyelitis. Case report.

Konstantinos D Stathopoulos1, Efthymia Giannitsioti2, Archondoula N Fragkou3, Aristides B Zoubos1, Panagiotis J Papaggelopoulos1, Grigoris Skarantavos1.   

Abstract

We report the case of a man with osteolytic lesions of the right mandible due to chronic osteomyelitis, with delayed healing after six months of antibiotic therapy. The patient received off-label therapy with strontium ranelate, with significant radiological improvement of his condition after 3 months.

Entities:  

Keywords:  bone healing; jaw; osteomyelitis; strontium ranelate

Year:  2014        PMID： 25002884      PMCID： PMC4064446     

Source DB:  PubMed          Journal:  Clin Cases Miner Bone Metab        ISSN： 1724-8914


  23 in total

1.  Effect of strontium ranelate on fracture healing in the osteoporotic rats.

Authors:  Kutay Engin Ozturan; Berfu Demir; Istemi Yucel; Husamettin Cakıcı; Fahri Yilmaz; Ali Haberal
Journal:  J Orthop Res       Date:  2010-08-19       Impact factor: 3.494

2.  Osteoblasts play key roles in the mechanisms of action of strontium ranelate.

Authors:  T C Brennan; M S Rybchyn; W Green; S Atwa; A D Conigrave; R S Mason
Journal:  Br J Pharmacol       Date:  2009-06-25       Impact factor: 8.739

3.  Bone material quality in transiliac bone biopsies of postmenopausal osteoporotic women after 3 years of strontium ranelate treatment.

Authors:  Paul Roschger; Inderchand Manjubala; Norbert Zoeger; Florian Meirer; Rolf Simon; Chenghao Li; Nadja Fratzl-Zelman; Barbara M Misof; Eleftherios P Paschalis; Christina Streli; Peter Fratzl; Klaus Klaushofer
Journal:  J Bone Miner Res       Date:  2010-04       Impact factor: 6.741

4.  Strontium ranelate reduces the risk of nonvertebral fractures in postmenopausal women with osteoporosis: Treatment of Peripheral Osteoporosis (TROPOS) study.

Authors:  J Y Reginster; E Seeman; M C De Vernejoul; S Adami; J Compston; C Phenekos; J P Devogelaer; M Diaz Curiel; A Sawicki; S Goemaere; O H Sorensen; D Felsenberg; P J Meunier
Journal:  J Clin Endocrinol Metab       Date:  2005-02-22       Impact factor: 5.958

5.  Efficacy and safety of strontium ranelate in the treatment of osteoporosis in men.

Authors:  J-M Kaufman; M Audran; G Bianchi; V Braga; M Diaz-Curiel; R M Francis; S Goemaere; R Josse; S Palacios; J D Ringe; D Felsenberg; S Boonen
Journal:  J Clin Endocrinol Metab       Date:  2013-01-22       Impact factor: 5.958

6.  Histomorphometric and microCT analysis of bone biopsies from postmenopausal osteoporotic women treated with strontium ranelate.

Authors:  Monique E Arlot; Yebin Jiang; Harry K Genant; Jenny Zhao; Brigitte Burt-Pichat; Jean-Paul Roux; Pierre D Delmas; Pierre J Meunier
Journal:  J Bone Miner Res       Date:  2008-02       Impact factor: 6.741

7.  The calcium-sensing receptor (CaR) is involved in strontium ranelate-induced osteoblast proliferation.

Authors:  Naibedya Chattopadhyay; Stephen J Quinn; Olga Kifor; Chianping Ye; Edward M Brown
Journal:  Biochem Pharmacol       Date:  2007-04-27       Impact factor: 5.858

8.  The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis.

Authors:  Pierre J Meunier; Christian Roux; Ego Seeman; Sergio Ortolani; Janusz E Badurski; Tim D Spector; Jorge Cannata; Adam Balogh; Ernst-Martin Lemmel; Stig Pors-Nielsen; René Rizzoli; Harry K Genant; Jean-Yves Reginster
Journal:  N Engl J Med       Date:  2004-01-29       Impact factor: 91.245

9.  Strontium ranelate treatment improves trabecular and cortical intrinsic bone tissue quality, a determinant of bone strength.

Authors:  Patrick Ammann; Isabelle Badoud; Sébastien Barraud; Romain Dayer; René Rizzoli
Journal:  J Bone Miner Res       Date:  2007-09       Impact factor: 6.741

10.  Chronic mandibular osteomyelitis with suspected underlying synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome: a case report.

Authors:  Yumi Mochizuki; Ken Omura; Hideaki Hirai; Takuma Kugimoto; Toshimitu Osako; Takahide Taguchi
Journal:  J Inflamm Res       Date:  2012-02-27
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  1 in total

1.  Strontium ranelate stimulates trabecular bone formation in a rat tibial bone defect healing process.

Authors:  C Lavet; G Mabilleau; D Chappard; R Rizzoli; P Ammann
Journal:  Osteoporos Int       Date:  2017-09-28       Impact factor: 4.507
  1 in total

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