Literature DB >> 25001974

PPI therapy. The small bowel, low-dose aspirin and PPIs--should we be concerned?

Angel Lanas1, Carlos Sostres1.   

Abstract

A new study suggests that co-prescription of low-dose aspirin and PPIs increases the incidence of small-bowel mucosal breaks. Should we be concerned about the potential negative interactions of these drugs? Or is the balance of evidence still substantially tipped towards the need for PPIs to protect against aspirin-induced upper gastrointestinal damage?

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Year:  2014        PMID: 25001974     DOI: 10.1038/nrgastro.2014.120

Source DB:  PubMed          Journal:  Nat Rev Gastroenterol Hepatol        ISSN: 1759-5045            Impact factor:   46.802


  2 in total

1.  Protons pump inhibitor treatment and lower gastrointestinal bleeding: Balancing risks and benefits.

Authors:  Alberto Lué; Angel Lanas
Journal:  World J Gastroenterol       Date:  2016-12-28       Impact factor: 5.742

2.  Initial Steps to Prevent Nonsteroidal Anti-Inflammatory Drug- or Aspirin-Induced Enteropathy: Long-Term Outcome Data.

Authors:  In Seok Lee; Yu Kyung Cho
Journal:  Gut Liver       Date:  2015-11-23       Impact factor: 4.519

  2 in total

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