Cofactor levels of mono- and diamine oxidase in atopic eczema.

We have recently shown that increased plasma histamine levels were associated with significantly lowered diamine and type B monoamine oxidase activities in platelet rich plasma of atopic eczema patients. We now report almost normal cofactor (pyridoxal phosphate and Cu2+) levels for diamine oxidase but lowered cofactor (flavin adenine dinucleotide and Fe2+) levels for type B monoamine oxidase.