Literature DB >> 24998939

Mathematical models in drug delivery: how modeling has shaped the way we design new drug delivery systems.

Nicholas A Peppas1, Balaji Narasimhan2.   

Abstract

In this review we present some of the seminal contributions that have established the mathematical foundations of controlled drug delivery and led to the modern models. Mathematical modeling is no longer just a dry exercise in generating more and more complex models or a parametric fitting process, but rather an advanced analysis that can lead to a priori examination of a release/delivery process or a series of design equations that help the practitioner achieve a better formulation.
Copyright © 2014 Elsevier B.V. All rights reserved.

Keywords:  Controlled release; Diffusion; Dissolution; Erosion; Mathematical modeling; Swelling

Mesh：

Substances：

Year:  2014        PMID： 24998939     DOI： 10.1016/j.jconrel.2014.06.041

Source DB:  PubMed          Journal:  J Control Release        ISSN： 0168-3659            Impact factor:   9.776


  53 in total

Review 1.  Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release.

Authors:  Nazila Kamaly; Basit Yameen; Jun Wu; Omid C Farokhzad
Journal:  Chem Rev       Date:  2016-02-08       Impact factor: 60.622

2.  The role of hydrophobic modification on hyaluronic acid dynamics and self-assembly.

Authors:  William M Payne; Denis Svechkarev; Alexander Kyrychenko; Aaron M Mohs
Journal:  Carbohydr Polym       Date:  2017-11-08       Impact factor: 9.381

Review 3.  Mathematical models of the steps involved in the systemic delivery of a chemotherapeutic to a solid tumor: From circulation to survival.

Authors:  Martin B Ulmschneider; Peter C Searson
Journal:  J Control Release       Date:  2015-06-20       Impact factor: 9.776

Review 4.  Engineered microscale hydrogels for drug delivery, cell therapy, and sequencing.

Authors:  Marissa E Wechsler; Regan E Stephenson; Andrew C Murphy; Heidi F Oldenkamp; Ankur Singh; Nicholas A Peppas
Journal:  Biomed Microdevices       Date:  2019-03-23       Impact factor: 2.838

5.  Design of PLGA-Based Drug Delivery Systems Using a Physically-Based Sustained Release Model.

Authors:  Stijn H S Koshari; Xutao Shi; Linda Jiang; Debby Chang; Karthikan Rajagopal; Abraham M Lenhoff; Norman J Wagner
Journal:  J Pharm Sci       Date:  2021-09-11       Impact factor: 3.534

6.  Formulation and Pharmacokinetic Evaluation of Ethyl Cellulose/HPMC-Based Oral Expandable Sustained Release Dosage of Losartan Potassium.

Authors:  Taha Umair Wani; Abdul Aala Fazli; Syed Naiem Raza; Nisar Ahmad Khan; Faheem A Sheikh
Journal:  AAPS PharmSciTech       Date:  2022-06-08       Impact factor: 3.246

7.  Poly(3-hydroxybutyrate)/metribuzin formulations: characterization, controlled release properties, herbicidal activity, and effect on soil microorganisms.

Authors:  Tatiana Volova; Natalia Zhila; Evgeniy Kiselev; Svetlana Prudnikova; Olga Vinogradova; Elena Nikolaeva; Anna Shumilova; Anna Shershneva; Ekaterina Shishatskaya
Journal:  Environ Sci Pollut Res Int       Date:  2016-09-15       Impact factor: 4.223

8.  Hydroxypropyl methylcellulose-based controlled release dosage by melt extrusion and 3D printing: Structure and drug release correlation.

Authors:  Jiaxiang Zhang; Weiwei Yang; Anh Q Vo; Xin Feng; Xingyou Ye; Dong Wuk Kim; Michael A Repka
Journal:  Carbohydr Polym       Date:  2017-08-18       Impact factor: 9.381

Review 9.  Translational Applications of Hydrogels.

Authors:  Santiago Correa; Abigail K Grosskopf; Hector Lopez Hernandez; Doreen Chan; Anthony C Yu; Lyndsay M Stapleton; Eric A Appel
Journal:  Chem Rev       Date:  2021-05-03       Impact factor: 60.622

10.  Electrospun Aspirin/Eudragit/Lipid Hybrid Nanofibers for Colon-targeted Delivery Using an Energy-saving Process.

Authors:  Yibin Wang; Liang Tian; Tianhao Zhu; Jing Mei; Zezhong Chen; Deng-Guang Yu
Journal:  Chem Res Chin Univ       Date:  2021-03-31       Impact factor: 1.307
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