| Literature DB >> 24998185 |
Patrick W Oakes1, Margaret L Gardel2.
Abstract
Focal adhesion assembly and maturation often occurs concomitantly with changes in force generated within the cytoskeleton or extracellular matrix. To coordinate focal adhesion dynamics with force, it has been suggested that focal adhesion dynamics are mechanosensitive. This review discusses current understanding of the regulation of focal adhesion assembly and force transmission, and the limits to which we can consider focal adhesion plaques as mechanosensitive entities.Entities:
Mesh:
Year: 2014 PMID: 24998185 PMCID: PMC4459577 DOI: 10.1016/j.ceb.2014.06.003
Source DB: PubMed Journal: Curr Opin Cell Biol ISSN: 0955-0674 Impact factor: 8.382