| Literature DB >> 24996060 |
Anne Gärtner1, Stefan Muller2.
Abstract
In this issue of Molecular Cell, Guo et al. (2014) report that misfolded or aggregated nuclear proteins, such as pathogenic polyQ proteins, are cleared by a SUMO-dependent quality control pathway, which involves the E3 SUMO ligase PML and the SUMO-targeted ubiquitin ligase RNF4.Entities:
Mesh：
Year: 2014 PMID： 24996060 DOI： 10.1016/j.molcel.2014.06.022
Source DB: PubMed Journal: Mol Cell ISSN： 1097-2765 Impact factor: 17.970