Literature DB >> 24995526

Understanding the complexity of the immune system during pregnancy.

Karen Racicot1, Ja-Young Kwon, Paulomi Aldo, Michelle Silasi, Gil Mor.   

Abstract

Progress in our understanding of the role of the maternal immune system during healthy pregnancy will help us better understand the role of the immune system in adverse pregnancy outcomes. In this review, we discuss our present understanding of the 'immunity of pregnancy' in the context of the response to cervical and placental infections and how these responses affect both the mother and the fetus. We discuss novel and challenging concepts that help explain the immunological aspects of pregnancy and how the mother and fetus respond to infection.
© 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  Immune regulation; macrophages; pregnancy; trophoblast

Mesh:

Year:  2014        PMID: 24995526      PMCID: PMC6800182          DOI: 10.1111/aji.12289

Source DB:  PubMed          Journal:  Am J Reprod Immunol        ISSN: 1046-7408            Impact factor:   3.886


  88 in total

1.  Deficiency of decidual IL-10 in first trimester missed abortion: a lack of correlation with the decidual immune cell profile.

Authors:  Michael Plevyak; Nazeeh Hanna; Sandra Mayer; Shaun Murphy; Halit Pinar; Loren Fast; Christi Ekerfelt; Jan Ernerudh; Goran Berg; Leif Matthiesen; Surendra Sharma
Journal:  Am J Reprod Immunol       Date:  2002-04       Impact factor: 3.886

2.  Placental inflammation and viral infection are implicated in second trimester pregnancy loss.

Authors:  Sindhu K Srinivas; Yujie Ma; Mary D Sammel; Doris Chou; Cindy McGrath; Samuel Parry; Michal A Elovitz
Journal:  Am J Obstet Gynecol       Date:  2006-09       Impact factor: 8.661

3.  Importance of uterine cell death, renewal, and their hormonal regulation in hamsters that show progesterone-dependent implantation.

Authors:  Qian Zhang; Bibhash C Paria
Journal:  Endocrinology       Date:  2006-02-09       Impact factor: 4.736

Review 4.  Uterine NK cells, spiral artery modification and the regulation of blood pressure during mouse pregnancy.

Authors:  Suzanne D Burke; Valerie F Barrette; Jonathan Gravel; Alexandra L I Carter; Kota Hatta; Jianhong Zhang; Zhilin Chen; Ester Leno-Durán; Juares Bianco; Sean Leonard; Coral Murrant; Michael A Adams; B Anne Croy
Journal:  Am J Reprod Immunol       Date:  2010-02-17       Impact factor: 3.886

Review 5.  What is new in the treatment of multiple sclerosis?

Authors:  B Weinstock-Guttman; L D Jacobs
Journal:  Drugs       Date:  2000-03       Impact factor: 9.546

6.  Sex hormone regulation of innate immunity in the female reproductive tract: the role of epithelial cells in balancing reproductive potential with protection against sexually transmitted pathogens.

Authors:  Charles R Wira; John V Fahey; Mimi Ghosh; Mickey V Patel; Danica K Hickey; Daniel O Ochiel
Journal:  Am J Reprod Immunol       Date:  2010-03-29       Impact factor: 3.886

7.  Suppressor of cytokine signaling-1 is essential for suppressing dendritic cell activation and systemic autoimmunity.

Authors:  Toshikatsu Hanada; Hiroki Yoshida; Seiya Kato; Kentaro Tanaka; Kohsuke Masutani; Jun Tsukada; Yoshio Nomura; Hiromitsu Mimata; Masato Kubo; Akihiko Yoshimura
Journal:  Immunity       Date:  2003-09       Impact factor: 31.745

8.  The transcriptome of the fetal inflammatory response syndrome.

Authors:  Sally A Madsen-Bouterse; Roberto Romero; Adi L Tarca; Juan Pedro Kusanovic; Jimmy Espinoza; Chong Jai Kim; Jung-Sun Kim; Samuel S Edwin; Ricardo Gomez; Sorin Draghici
Journal:  Am J Reprod Immunol       Date:  2010-01       Impact factor: 3.886

9.  Elevation of tumor necrosis factor-alpha in cerebrospinal fluid of autistic children.

Authors:  Michael G Chez; Tim Dowling; Pikul B Patel; Pavan Khanna; Matt Kominsky
Journal:  Pediatr Neurol       Date:  2007-06       Impact factor: 3.372

10.  The Human Placenta Project: placental structure, development, and function in real time.

Authors:  A E Guttmacher; Y T Maddox; C Y Spong
Journal:  Placenta       Date:  2014-03-06       Impact factor: 3.481

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  113 in total

1.  "I Did Not Want to Give Birth to a Child Who has HIV": Experiences Using PrEP During Pregnancy Among HIV-Uninfected Kenyan Women in HIV-Serodiscordant Couples.

Authors:  Jillian Pintye; Kristin M Beima-Sofie; Grace Kimemia; Kenneth Ngure; Susan Brown Trinidad; Renee A Heffron; Jared M Baeten; Josephine Odoyo; Nelly Mugo; Elizabeth A Bukusi; Maureen C Kelley; Grace C John-Stewart
Journal:  J Acquir Immune Defic Syndr       Date:  2017-11-01       Impact factor: 3.731

2.  The maternal plasma proteome changes as a function of gestational age in normal pregnancy: a longitudinal study.

Authors:  Roberto Romero; Offer Erez; Eli Maymon; Piya Chaemsaithong; Zhonghui Xu; Percy Pacora; Tinnakorn Chaiworapongsa; Bogdan Done; Sonia S Hassan; Adi L Tarca
Journal:  Am J Obstet Gynecol       Date:  2017-03-03       Impact factor: 8.661

3.  Relevance of placental type I interferon beta regulation for pregnancy success.

Authors:  Ja-Young Kwon; Paulomi Aldo; Yuan You; Jiahui Ding; Karen Racicot; Xiaoyan Dong; John Murphy; Guy Glukshtad; Michelle Silasi; Jian Peng; Li Wen; Vikki M Abrahams; Roberto Romero; Gil Mor
Journal:  Cell Mol Immunol       Date:  2018-06-15       Impact factor: 11.530

4.  Maternal Gestational Immune Response and Autism Spectrum Disorder Phenotypes at 7 Years of Age in the Seychelles Child Development Study.

Authors:  Jessica L Irwin; Alison J Yeates; Maria S Mulhern; Emeir M McSorley; J J Strain; Gene E Watson; Katherine Grzesik; Sally W Thurston; Tanzy M Love; Tristram H Smith; Daniel W Mruzek; Conrad F Shamlaye; Catriona Monthy; Gary J Myers; Philip W Davidson; Edwin van Wijngaarden
Journal:  Mol Neurobiol       Date:  2018-11-14       Impact factor: 5.590

Review 5.  Influenza immunization during pregnancy: Benefits for mother and infant.

Authors:  Isaac G Sakala; Yoshikazu Honda-Okubo; Johnson Fung; Nikolai Petrovsky
Journal:  Hum Vaccin Immunother       Date:  2016-08-05       Impact factor: 3.452

6.  Maternal immune markers during pregnancy and child neurodevelopmental outcomes at age 20 months in the Seychelles Child Development Study.

Authors:  Jessica L Irwin; Emeir M McSorley; Alison J Yeates; Maria S Mulhern; J J Strain; Gene E Watson; Katherine Grzesik; Sally W Thurston; Tanzy M Love; Tristram H Smith; Karin Broberg; Conrad F Shamlaye; Gary J Myers; Philip W Davidson; Edwin van Wijngaarden
Journal:  J Neuroimmunol       Date:  2019-08-14       Impact factor: 3.478

7.  HIV-Uninfected Kenyan Adolescent and Young Women Share Perspectives on Using Pre-Exposure Prophylaxis During Pregnancy.

Authors:  Jillian Pintye; Kristin M Beima-Sofie; Pamela A Makabong'O; Anne Njoroge; Susan Brown Trinidad; Renee A Heffron; Jared M Baeten; Connie Celum; Daniel Matemo; John Kinuthia; Maureen C Kelley; Grace C John-Stewart
Journal:  AIDS Patient Care STDS       Date:  2018-07-23       Impact factor: 5.078

8.  Fetal death: an extreme manifestation of maternal anti-fetal rejection.

Authors:  Kia Lannaman; Roberto Romero; Tinnakorn Chaiworapongsa; Yeon Mee Kim; Steven J Korzeniewski; Eli Maymon; Nardhy Gomez-Lopez; Bogdan Panaitescu; Sonia S Hassan; Lami Yeo; Bo Hyun Yoon; Chong Jai Kim; Offer Erez
Journal:  J Perinat Med       Date:  2017-10-26       Impact factor: 1.901

9.  Fetal Protection : The Roles of Social Learning and Innate Food Aversions in South India.

Authors:  Caitlyn D Placek; Edward H Hagen
Journal:  Hum Nat       Date:  2015-09

Review 10.  The First Microbial Colonizers of the Human Gut: Composition, Activities, and Health Implications of the Infant Gut Microbiota.

Authors:  Christian Milani; Sabrina Duranti; Francesca Bottacini; Eoghan Casey; Francesca Turroni; Jennifer Mahony; Clara Belzer; Susana Delgado Palacio; Silvia Arboleya Montes; Leonardo Mancabelli; Gabriele Andrea Lugli; Juan Miguel Rodriguez; Lars Bode; Willem de Vos; Miguel Gueimonde; Abelardo Margolles; Douwe van Sinderen; Marco Ventura
Journal:  Microbiol Mol Biol Rev       Date:  2017-11-08       Impact factor: 11.056

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