Sanyuktha Shetty1, Sharath K2, Biju Thomas3, Nitin Shetty4, Arvind Shetty5, Devanand Shetty6. 1. Senior Lecturer, Department of Periodontics, Dr. D.Y. Patil Dental College & Hospital , Nerul, Navi Mumbai, India . 2. Professor and Head, Department of Periodontics, Srinivas Institute of Dental Sciences , Mukka, Karnataka, India . 3. Professor and Head, Department of Periodontics, A.B. Shetty Memorial Institute of Dental Sciences , Deralakatte, Mangalore, Karnataka, India . 4. Senior Lecturer, Department of Prosthodontics, Dr. D.Y. Patil Dental College & Hospital , Nerul, Navi Mumbai, India . 5. Professor and Head, Department of Periodontics, Dr. D.Y. Patil Dental College & Hospital , Nerul, Navi Mumbai, India . 6. Professor, Department of Periodontics, Dr. D.Y. Patil Dental College & Hospital , Nerul, Navi Mumbai, India .
Abstract
AIM: To evaluate and compare the clinical effects of ibuprofen and diclofenac sodium on bleeding during periodontal surgery. MATERIALS AND METHODS:Thirteen medically healthy men and women of mean age 37.5±17.67 (mean age± standard deviation) were selected for the study. All the subjects were divided into three groups: control (C) and test groups (T1) and (T2). Each subject of T1 group and T2 group was given ibuprofen and diclofenac sodium respectively, prior to surgery. Bleeding times of patients were recorded prior to performance of periodontal flap surgical procedures. RESULTS: It was found that there was increased bleeding time and increased peri-operative bleeding when ibuprofen and diclofenac sodium were taken prior to surgery and this was statistically significant. (2.5538 (T1), 1.8385 (T2) versus 1.2385 (C) minute, p= .001) (mean blood loss) and (62.0325 ± 9.0594 (T1), 51.082 ± 9.792 (T2) versus 37.4992 ± 5.99 (C) millilitre, p = .000). CONCLUSION: The findings of this study suggested that pre-operative administration of ibuprofen and diclofenac sodium could increase bleeding time and peri - operative blood loss.
RCT Entities:
AIM: To evaluate and compare the clinical effects of ibuprofen and diclofenac sodium on bleeding during periodontal surgery. MATERIALS AND METHODS: Thirteen medically healthy men and women of mean age 37.5±17.67 (mean age± standard deviation) were selected for the study. All the subjects were divided into three groups: control (C) and test groups (T1) and (T2). Each subject of T1 group and T2 group was given ibuprofen and diclofenac sodium respectively, prior to surgery. Bleeding times of patients were recorded prior to performance of periodontal flap surgical procedures. RESULTS: It was found that there was increased bleeding time and increased peri-operative bleeding when ibuprofen and diclofenac sodium were taken prior to surgery and this was statistically significant. (2.5538 (T1), 1.8385 (T2) versus 1.2385 (C) minute, p= .001) (mean blood loss) and (62.0325 ± 9.0594 (T1), 51.082 ± 9.792 (T2) versus 37.4992 ± 5.99 (C) millilitre, p = .000). CONCLUSION: The findings of this study suggested that pre-operative administration of ibuprofen and diclofenac sodium could increase bleeding time and peri - operative blood loss.
Entities:
Keywords:
Blood loss; Diclofenac sodium; Ibuprofen; Periodontal flap surgery